ArticleBiomedical optics express2018
Quantitative characterization of bovine serum albumin thin-films using terahertz spectroscopy and machine learning methods.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 43 citations in OpenAlex.
- The optimal substrate choice for effective biosensors based on THz metasurfaces.Scientific reports · 2025Article
- Recent progress in terahertz sensors based on graphene metamaterials.Discover nano · 2025Review
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- Double-Strip Array-Based Metasurfaces with BICs for Terahertz Thin Membrane Detection.Micromachines · 2023Article
- Study on the detection method of biological characteristics of hepatoma cells based on terahertz time-domain spectroscopy.Biomedical optics express · 2023Article
- Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses.Frontiers in bioengineering and biotechnology · 2023Review
- Terahertz time-domain attenuated total reflection spectroscopy integrated with a microfluidic chip.Frontiers in bioengineering and biotechnology · 2023Article
- Label-free study on the effect of a bioactive constituent on glioma cells in vitro using terahertz ATR spectroscopy.Biomedical optics express · 2022Article
- Machine Learning Techniques for THz Imaging and Time-Domain Spectroscopy.Sensors (Basel, Switzerland) · 2021Review
- Quantitative analysis of homocysteine in liquid by terahertz spectroscopy.Biomedical optics express · 2020Article
- Qualitative and quantitative detection of liver injury with terahertz time-domain spectroscopy.Biomedical optics express · 2020Article
- Ultrasensitive THz biosensor for PCR-free cDNA detection based on frequency selective surfaces.Biomedical optics express · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of new spectral analysis methods in bio thin-film detection has generated intense interest in terahertz (THz) spectroscopy and its application in a wide range of fields. In this paper, it is the first time that machine learning methods are applied to the quantitative characterization of bovine serum albumin (BSA) deposited thin-films detected by terahertz time-domain spectroscopy. The spectra data of BSA thin-films prepared by solutions with concentrations ranging from 0.5 to 35 mg/ml are analyzed using the support vector regression method to learn the underlying model of the frequency against the target concentration. The learned mode successfully predicts the concentrations of the unknown test samples with a coefficient of determination R
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