ArticleJournal of periodontal & implant science2018
The effects of ozone therapy as an adjunct to the surgical treatment of peri-implantitis.
Article in Journal of periodontal & implant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03018795 (The Effect of Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis: A Randomized Controlled Clinical Trial
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy of surgical methods for peri-implantitis: a systematic review and network meta-analysis.BMC oral health · 2023Pooled it
- Surface decontamination protocols for surgical treatment of peri-implantitis: A systematic review with meta-analysis.Clinical oral implants research · 2022Pooled it
- Efficacy of alternative or adjunctive measures to conventional non-surgical and surgical treatment of peri-implant mucositis and peri-implantitis: a systematic review and meta-analysis.International journal of implant dentistry · 2021Pooled it
- Efficacy of different nonsurgical treatments for peri-implantitis: a multi-arm randomized controlled clinical trial.Scientific reports · 2026Trial
- Ozonized Hydrogel and Chlorhexidine Gel for Peri-Implant Mucositis: A 24-Month Randomized Controlled Trial.Oral diseases · 2026Trial
- Effects of ozone therapy on postoperative pain, swelling, and trismus caused by surgical extraction of unerupted lower third molars: a double-blinded split-mouth randomized controlled trial.Medicina oral, patologia oral y cirugia bucal · 2025Trial
- The Gaseous Ozone Therapy as a Promising Antiseptic Adjuvant of Periodontal Treatment: A Randomized Controlled Clinical Trial.International journal of environmental research and public health · 2022Trial
- Adjunctive effect of soft tissue grafting in the surgical treatment of peri-implantitis: clinical and radiographic outcomes from a preclinical canine experiment.Journal of periodontal & implant science · 2026Article
- Mucositis and Peri-Implant Disease Treatment with Chitosan and Titanium Brushes: A Systematic Review.Journal of clinical medicine · 2025Review
- The Impact of Ozone on Periodontal Cell Line Viability and Function.Current issues in molecular biology · 2025Review
- The Management of Necrotizing Gingivitis in Paediatric Patients: A Scoping Review and Two Case Reports.Children (Basel, Switzerland) · 2024Article
- Efficacy of a Solution Containing 33% Trichloroacetic Acid and Hydrogen Peroxide in Decontaminating Machined vs. Sand-Blasted Acid-Etched Titanium Surfaces.Journal of functional biomaterials · 2024Article
- Surgical regenerative methods for peri-implantitis treatment: A systematic review and meta-analysis.Journal of advanced periodontology & implant dentistry · 2024Article
- Is Ozone a Valid Adjuvant Therapy for Periodontitis and Peri-Implantitis? A Systematic Review.Journal of personalized medicine · 2023Review
- Efficacy Ozone Therapy in Reducing Periodontal Disease.Materials (Basel, Switzerland) · 2023Article
- Ozonized Hydrogels vs. 1% Chlorhexidine Gel for the Clinical and Domiciliary Management of Peri-Implant Mucositis: A Randomized Clinical Trial.Journal of clinical medicine · 2023Article
- Potential Clinical Applications of Ozone Therapy in Dental Specialties-A Literature Review, Supported by Own Observations.International journal of environmental research and public health · 2023Review
- A Narrative Review on Means to Promote Oxygenation and Angiogenesis in Oral Wound Healing.Bioengineering (Basel, Switzerland) · 2022Review
- Application of Selected Nanomaterials and Ozone in Modern Clinical Dentistry.Nanomaterials (Basel, Switzerland) · 2021Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe decontamination procedure is a challenging aspect of surgical regenerative therapy (SRT) of peri-implantitis that affects its success. The purpose of the present study was to determine the impact of additional topical gaseous ozone therapy on the decontamination of implant surfaces in SRT of peri-implantitis.
methodsA total of 41 patients (22 males, 19 females; mean age, 53.55±8.98 years) with moderate or advanced peri-implantitis were randomly allocated to the test group (ozone group) with the use of sterile saline with additional ozone therapy or the control group with sterile saline alone for decontamination of the implant surfaces in SRT of peri-implantitis. Clinical and radiographic outcomes were evaluated over a period of 12 months.
resultsAt the 12-month follow-up, the plaque and gingival index values were significantly better in the ozone group (
conclusionsImplant surface decontamination with the additional use of ozone therapy in SRT of peri-implantitis showed clinically and radiographically significant. Trial registry at ClinicalTrials.gov, NCT03018795.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.