Evidence map›Paper›PMID 29984037›Full record

ArticleImmune network2018

L1 Recombinant Proteins of HPV Tested for Antibody Forming Using Sera of HPV Quadrivalent Vaccine.

Begum Akuzum, Sinae Kim, Tam Thanh Nguyen, Jeawoo Hong, Siyoung Lee, Eunhye Kim, Joohee Kim, Yeook Choi, Hyunjhung Jhun, Youngmin Lee and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immune network, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Begum AkuzumLaboratory of Cytokine Immunology, Department of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.
Sinae KimCollege of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Tam Thanh NguyenCollege of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Jeawoo HongLaboratory of Cytokine Immunology, Department of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.
Siyoung LeeYbdYbiotech Research Center, Seoul 08589, Korea.
Eunhye KimCollege of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Joohee KimLaboratory of Cytokine Immunology, Department of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.
Yeook ChoiLaboratory of Cytokine Immunology, Department of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.
Hyunjhung JhunYbdYbiotech Research Center, Seoul 08589, Korea.
Youngmin LeeDepartment of Medicine, Pusan Paik Hospital, Inje University College of Medicine, Busan 47392, Korea.
Hyunwoo KimDivision of Nephrology, Department of Internal Medicine, Jeju National University School of Medicine, Jeju 63243, Korea.
Dong Hyun SohnDepartment of Microbiology and Immunology, Pusan National University School of Medicine, Yangsan 50612, Korea.
Soohyun KimLaboratory of Cytokine Immunology, Department of Biomedical Science and Technology, Konkuk University, Seoul 05029, Korea.
Konkuk University · KRAdbiotech (South Korea) · KRJeju National University · KRPusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus-like particles (VLPs) derived from human papillomavirus (HPV) L1 capsid proteins were used for HPV quadrivalent recombinant vaccine. The HPV quadrivalent vaccine is administrated in a 3-dose regimen of initial injection followed by subsequent doses at 2 and 6 months to prevent cervical cancer, vulvar, and vaginal cancers. The type 6, 11, 16, or 18 of HPV infection is associated with precancerous lesions and genital warts in adolescents and young women. The HPV vaccine is composed of viral L1 capsid proteins are produced in eukaryotic expression systems and purified in the form of VLPs. Four different the L1 protein of 3 different subtypes of HPV: HPV11, HPV16, and HPV18 were expressed in

Indexed as

Enzyme-linked immunosorbent assayL1 capsid proteinsPapillomaviridaeRecombinant proteinsWestern blot

Identifiers

PMID29984037
PMCPMC6026689
OpenAlexW2806080103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.