Evidence map›Paper›PMID 29984006›Full record

ArticleCase reports in critical care2018

Severe Progressive Diffuse Alveolar Hemorrhage in a Patient with Systemic Lupus Erythematosus.

Munenori Kusunoki, Takeshi Umegaki, Tomohiro Shoji, Kota Nishimoto, Natsuki Anada, Akiko Ando, Takeo Uba, Kanako Oku, Saya Hakata, Satoshi Hagihira and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Hemoptysis Due to Diffuse Alveolar Hemorrhage.Journal of education & teaching in emergency medicine · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Munenori KusunokiDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Takeshi UmegakiDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.ORCID 0000-0001-6113-6444
Tomohiro ShojiDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Kota NishimotoDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Natsuki AnadaDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Akiko AndoDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Takeo UbaDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Kanako OkuDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Saya HakataDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Satoshi HagihiraDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Takahiko KamibayashiDepartment of Anesthesiology, Kansai Medical University Hospital, Osaka, Japan.
Kansai Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse alveolar hemorrhage (DAH) refers to the effusion of blood into the alveoli due to damaged pulmonary microvasculature. The ensuing alveolar collapse can lead to severe hypoxemia with poor prognosis. In these cases, it is crucial to provide respiratory care for hypoxemia in addition to treating the underlying disease. Here, we describe our experience with a case involving a 46-year-old woman with severe DAH-induced hypoxemia accompanying systemic lupus erythematosus (SLE). Mechanical ventilation was managed using airway pressure release ventilation (APRV) after intubation. Through APRV-based respiratory care and treatment of the underlying disease, hemoptysis was eliminated and oxygenation improved. The patient did not experience significant barotrauma and was successfully weaned from mechanical ventilation after 25 days in the intensive care unit. This case demonstrates that APRV-based control for respiratory management can inhibit the effusion of blood into the alveoli and achieve mechanical hemostasis, as well as mitigate alveolar collapse. APRV may be a useful method for respiratory care in patients with severe DAH-induced hypoxemia.

Identifiers

PMID29984006
PMCPMC6011174
OpenAlexW2805534445

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.