Evidence map›Paper›PMID 29983910›Full record

ArticleF1000Research2017

Hepatic deletion of p110α and p85α results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase activity.

Aditi Chaudhari, Katarina Ejeskär, Yvonne Wettergren, C Ronald Kahn, Victoria Rotter Sopasakis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. PI3Kinases in Diabetes Mellitus and Its Related Complications.International journal of molecular sciences · 2018
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Aditi ChaudhariWallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.
Katarina EjeskärInstitute of Health and Education, Translational Medicine, University of Skövde, Skövde, Sweden.
Yvonne WettergrenDepartment of Surgery, University of Gothenburg, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.
C Ronald KahnJoslin Diabetes Center and Harvard Medical School, One Joslin Place, Boston, MA, USA.
Victoria Rotter SopasakisWallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-1012-1952
Joslin Diabetes Center · USSahlgrenska University Hospital · SEUniversity of Gothenburg · SEUniversity of Skövde · SE

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
Insulin Receptor Substrates and Insulin ActionR01DK033201 · NIDDK · JOSLIN DIABETES CENTER · PI KAHN, C RONALD · 1986 to 2016
$10.6M
Role of PI 3-Kinase Isoforms in Insulin ActionR01DK055545 · NIDDK · JOSLIN DIABETES CENTER · PI KAHN, C RONALD · 1999 to 2020
$8.3M
NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R01 DK033201NIDDK NIH HHS R01 DK055545
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

5-bisphosphate 3-kinaseglucose intoleranceinsulin receptor substrateinsulin resistancep110p85phosphatidylinositol-4

Identifiers

PMID29983910
PMCPMC6020741
OpenAlexW2753800723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.