Evidence map›Paper›PMID 29983839›Full record

ArticleBiomicrofluidics2018

Virtual vortex gear: Unique flow patterns driven by microfluidic inertia leading to pinpoint injection.

Chia-Hung Dylan Tsai, Toshio Takayama, Yuta Shimozyo, Takayuki Akai, Makoto Kaneko

Abstract read
In one paragraph

Article in Biomicrofluidics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chia-Hung Dylan TsaiDepartment of Mechanical Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan.ORCID 0000-0002-8840-3984
Toshio TakayamaDepartment of Mechanical Engineering, Osaka University, Suita 565-0871, Japan.
Yuta ShimozyoDepartment of Mechanical Engineering, Osaka University, Suita 565-0871, Japan.
Takayuki AkaiDepartment of Mechanical Engineering, Osaka University, Suita 565-0871, Japan.
Makoto KanekoDepartment of Mechanical Engineering, Osaka University, Suita 565-0871, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An interesting phenomenon that vortices are sequentially generated on a microfluidic chip is investigated in this paper. The direction of every two adjacent vortices is opposite to each other, like a set of gears, and thus is named virtual vortex gear (VVG). Both experiments and computational simulations were conducted in order to make clear the mechanism of VVG. The experimental results show that only the flow from a particular point would form vortices and enter the target chamber. A technique of inverse mapping is proposed based on the phenomenon and it demonstrates that only a pinpoint injection is sufficient to control the contents of a microfluidic chamber. VVG can significantly reduce the volume of chemical usage in biological research and has potential for other on-chip applications, such as mixing and valving.

Identifiers

PMID29983839
PMCPMC6010358

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.