Evidence map›Paper›PMID 29983838›Full record

ArticleBiomicrofluidics2018

Oscillating dispersed-phase co-flow microfluidic droplet generation: Multi-droplet size effect.

Amin Shams Khorrami, Pouya Rezai

Abstract read
In one paragraph

Article in Biomicrofluidics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amin Shams KhorramiDepartment of Mechanical Engineering, York University, Toronto, Ontario M3J 1P3, Canada.ORCID 0000-0002-0018-6381
Pouya RezaiDepartment of Mechanical Engineering, York University, Toronto, Ontario M3J 1P3, Canada.ORCID 0000-0002-5031-8063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Controllable generation of microdroplets at desired sizes and throughputs is important in many applications. Many biological assays require size-optimized droplets for effective encapsulation of analytes and reagents. To perform size optimization, different-size droplets must be generated from identical sources of samples to prevent potential cross-sample variations or other sources of error. In this paper, we introduce a novel alteration of the co-flow droplet generation technique to achieve multi-size generation of monodispersed droplets. Using a custom-made mechanism, we oscillate the disperse-phase (d-phase) flow nozzle perpendicular to the continuous phase (c-phase) flow in a co-flow channel. Oscillation of the d-phase nozzle introduces an additional lateral drag force to the growing droplets while exposing them to various levels of axial drag owing to the parabolic velocity distribution of the c-phase flow. Superimposing both effects results in simultaneous and repeatable generation of monodispersed droplets with different sizes. The effect of nozzle oscillation frequency (f = 0-15 Hz) on droplet generation at different d-phase (Q

Identifiers

PMID29983838
PMCPMC6005787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.