Evidence map›Paper›PMID 29983740›Full record

ArticleBiotechnology for biofuels2018

Stepwise metabolic engineering of

Lin Xu, Lian Wang, Xue-Rong Zhou, Wen-Chao Chen, Surinder Singh, Zhe Hu, Feng-Hong Huang, Xia Wan

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 36 citations in OpenAlex.

  1. Essential Biology of Lipid Droplets.Annual review of biochemistry · 2025
    Review
  2. Engineering caveolin-mediated endocytosis inSynthetic and systems biotechnology · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Lin Xu1Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, 430062 People's Republic of China.
Lian Wang *1Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, 430062 People's Republic of China.
Xue-Rong Zhou2CSIRO Agriculture & Food, Canberra, 2601 Australia.
Wen-Chao Chen1Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, 430062 People's Republic of China.
Surinder Singh2CSIRO Agriculture & Food, Canberra, 2601 Australia.
Zhe Hu6State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070 People's Republic of China.
Feng-Hong Huang1Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, 430062 People's Republic of China.
Xia Wan1Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, 430062 People's Republic of China.
Oil Crops Research Institute · CNCommonwealth Scientific and Industrial Research Organisation · AUChinese Academy of Agricultural Sciences · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTriacylglycerols (TAGs) rich in medium-chain fatty acids (MCFAs, C10-14 fatty acids) are valuable feedstocks for biofuels and chemicals. Natural sources of TAGs rich in MCFAs are restricted to a limited number of plant species, which are unsuitable for mass agronomic production. Instead, the modification of seed or non-seed tissue oils to increase MCFA content has been investigated. In addition, microbial oils are considered as promising sustainable feedstocks for providing TAGs, although little has been done to tailor the fatty acids in microbial TAGs.

resultsHere, we first assessed various wax synthase/acyl-coenzyme A:diacylglycerol acyltransferases, phosphatidic acid phosphatases, acyl-CoA synthetases as well as putative fatty acid metabolism regulators for producing high levels of TAGs in

conclusionsWe introduced a complete Kennedy pathway into non-oleaginous

Indexed as

Acyl-ACP thioesteraseAcyltransferaseEscherichia coliLipid dropletMedium-chain fatty acidTriacylglycerol

Identifiers

PMID29983740
PMCPMC6016142
OpenAlexW2810382848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.