Evidence map›Paper›PMID 29983600›Full record

ArticleJournal of blood medicine2018

Hematological abnormalities in HIV-antiretroviral therapy naïve clients as seen at an immune suppression syndrome clinic at Mbarara Regional Referral Hospital, southwestern Uganda.

Crispus Katemba, Conrad Muzoora, Enoch Muwanguzi, Bashir Mwambi, Christine Atuhairwe, Ivan M Taremwa

Open access · goldAbstract read
In one paragraph

Article in Journal of blood medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Crispus KatembaDepartment of Medical Laboratory Sciences, Mbarara University of Science and Technology, Mbarara, Uganda.
Conrad MuzooraDepartment of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Enoch MuwanguziDepartment of Medical Laboratory Sciences, Mbarara University of Science and Technology, Mbarara, Uganda.
Bashir MwambiInstitute of Allied Health Sciences, Clarke International University, Kampala, Uganda, imugisha@ymail.com.
Christine AtuhairweInstitute of Public Health and Management, Clarke International University, Kampala, Uganda.
Ivan M TaremwaInstitute of Allied Health Sciences, Clarke International University, Kampala, Uganda, imugisha@ymail.com.
Clarke International University · UGMbarara University of Science and Technology · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIM/

objectiveTo assess the common hematological abnormalities among HIV-antiretroviral therapy (ART) naïve clients attending an immune suppression syndrome (ISS) clinic at Mbarara Regional Referral Hospital (MRRH), southwestern Uganda. PATIENTS AND

methodsThis was a cross-sectional study carried out during the months of March to August 2016 at the ISS clinic of MRRH. We collected approximately 4.0 mL of EDTA anticoagulated blood samples, which were assayed for complete blood count, CD4+ cell count and thin film examination. Correlation of the hematological abnormalities with CD4+ cell counts was done using correlation coefficient (

resultsA total of 141 clients were enrolled. Of these, 67.38% (95/141) were anemic, 26.24% (40/141) had thrombocytopenia while 26.95% (38/141) had leucopenia. Of the 95 participants with anemia, 89.47% (85/95) presented with normocytic-normochromic anemia, 8.42% (8/95) with microcytic-hypochromic anemia and 2.11% (2/95) with macrocytic-hypochromic anemia. Anemia was not different across the several World Health Organization (WHO) stages of HIV infection disease progression (

conclusionPeople living with HIV/AIDS (PLWHIV/AIDS) ought to be routinely monitored and treated for the occurrence of hematological abnormalities. Early initiation of ART can help to prevent some hematological abnormalities.

Indexed as

anemiaantiretroviral therapyHIVleucopeniathrombocytopeniaUganda

Identifiers

PMID29983600
PMCPMC6027711
OpenAlexW2810105151

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.