Evidence map›Paper›PMID 29983392›Full record

ArticleDrug and alcohol dependence2018

Disturbances of postural sway components in cannabis users.

Amanda R Bolbecker, Deborah Apthorp, Ashley Schnakenberg Martin, Behdad Tahayori, Leah Moravec, Karen L Gomez, Brian F O'Donnell, Sharlene D Newman, William P Hetrick

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Amanda R BolbeckerDept. of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States; Dept. of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, United States; Larue D. Carter Memorial Hospital, Indianapolis, IN, United States; School of Psychology and Behavioural Science, University of New England, NSW, Australia. Electronic address: arhoskin@indiana.edu.
Deborah ApthorpSchool of Psychology and Behavioural Science, University of New England, NSW, Australia; Research School of Computer Science, Australian National University, ACT, Australia.
Ashley Schnakenberg MartinDept. of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States.
Behdad TahayoriDepartment of Biomedical Engineering, Florida International University, Miami, Florida, United States.
Leah MoravecDept. of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States.
Karen L GomezDept. of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States.
Brian F O'DonnellDept. of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States; Dept. of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, United States; Larue D. Carter Memorial Hospital, Indianapolis, IN, United States.
Sharlene D NewmanDept. of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States.
William P HetrickDept. of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States; Dept. of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, United States; Larue D. Carter Memorial Hospital, Indianapolis, IN, United States.
Indiana University Bloomington · USFlorida International University · USLarue Carter Hospital · USUniversity of New England · AU

Funding

Cerebellar timing dysfunction in schizophreniaR01MH074983 · NIMH · TRUSTEES OF INDIANA UNIVERSITY · PI HETRICK, WILLIAM P · 2006 to 2016
$3.6M
INTEGRATIVE PREDOCTORAL TRAINING IN DRUG ABUSE RESEARCH AT INDIANA UNIVERSITYT32DA024628 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI Andrea Grace Hohmann, Kenneth Mackie · 2008 to 2026
$3.1M
Graph Theoretic Analysis of Brain Networks in Cannabis UsersR21DA035493 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI O'DONNELL, BRIAN FRANCIS · 2014 to 2015
$426k
NIDA NIH HHS R21 DA035493NIDA NIH HHS T32 DA024628NIMH NIH HHS R01 MH074983
6 · The paper itself

Abstract

introductionA prominent effect of acute cannabis use is impaired motor coordination and driving performance. However, few studies have evaluated balance in chronic cannabis users, even though density of the CB1 receptor, which mediates the psychoactive effects of cannabis, is extremely high in brain regions critically involved in this fundamental behavior. The present study measured postural sway in regular cannabis users and used rambling and trembling analysis to quantify the integrity of central and peripheral nervous system contributions to the sway signal.

methodsPostural sway was measured in 42 regular cannabis users (CB group) and 36 non-cannabis users (N-CB group) by asking participants to stand as still as possible on a force platform in the presence and absence of motor and sensory challenges. Center of pressure (COP) path length was measured, and the COP signal was decomposed into rambling and trembling components. Exploratory correlational analyses were conducted between sway variables, cannabis use history, and neurocognitive function.

resultsThe CB group had significantly increased path length and increased trembling in the anterior-posterior (AP) direction. Exploratory correlational analyses suggested that AP rambling was significantly inversely associated with visuo-motor processing speed. DISCUSSION: Regular cannabis use is associated with increased postural sway, and this appears to be predominantly due to the trembling component, which is believed to reflect the peripheral nervous system's contribution to the sway signal.

Indexed as

AdolescentAdultCannabisFemaleHumansMaleMarijuana AbuseMarijuana SmokingPostural BalanceYoung AdultCannabinoidCannabisDelta-9-tetrahydrocannabinolEndocannabinoidMotor controlPostural swayPsychomotorRamblingTHCTrembling

Identifiers

PMID29983392
PMCPMC7185833
OpenAlexW2809550089

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.