ArticleClinical therapeutics2018
Hepatitis C Management Simplification From Test to Cure: A Framework for Primary Care Providers.
Article in Clinical therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Care strategies for pregnant people and women living with hepatitis C in North America.AJOG global reports · 2026Article
- Identifying Varying Influences on Eliminating Hepatitis C Across Medical Specialties.Journal of viral hepatitis · 2025Article
- Road to Hepatitis C Elimination in Israel: Improvements in Linkage to Care (2009-2020).Advances in therapy · 2025Article
- Understanding Users' Engagement in a Provider-Created Mobile App for Training to Advance Hepatitis C Care: Knowledge Assessment Survey Study.JMIR formative research · 2024Article
- Liver function tests in primary care provide a key opportunity to diagnose and engage patients with hepatitis C.Epidemiology and infection · 2022Article
- HCV reflex testing: A single-sample, low-contamination method that improves the diagnostic efficiency of HCV testing among patients in Alberta, Canada.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022Article
- Predictors of linkage to hepatitis C virus care among people living with HIV with hepatitis C infection and the impact of loss to HIV follow-up.Health science reports · 2022Article
- Economic impact of applying the AASLD-IDSA simplified treatment algorithm on the real-world management of hepatitis C.Journal of managed care & specialty pharmacy · 2022Article
- Efficacy and Safety of Glecaprevir/Pibrentasvir in Korean Patients with Chronic Hepatitis C: A Pooled Analysis of Five Phase II/III Trials.Gut and liver · 2021Article
- Cost Effectiveness of Screening for Hepatitis C Virus in Iraq in the Era of Simplified Testing and Treatment.PharmacoEconomics · 2021Article
- A hepatitis C elimination model in healthcare for the homeless organization: A novel reflexive laboratory algorithm and equity assessment.The International journal on drug policy · 2021Article
- Hepatitis C Virus Infection: What Are We Currently Doing in Latin America About WHO's Proposals for 2030?Clinical liver disease · 2021Review
- Safety of Patients with Hepatitis C Virus Treated with Glecaprevir/Pibrentasvir from Clinical Trials and Real-World Cohorts.Advances in therapy · 2021Article
- Can Telementoring Reduce Urban-Rural Disparities in Utilization of Direct-Acting Antiviral Agents?Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2021Article
- Changing Urban-Rural Disparities in the Utilization of Direct-Acting Antiviral Agents for Hepatitis C in U.S. Medicare Patients, 2014-2017.American journal of preventive medicine · 2021Article
- A Telementoring Program and Hepatitis C Virus Care in Rural Patients.Telemedicine reports · 2021Article
- Beyond clinical outcomes: the social and healthcare system implications of hepatitis C treatment.BMC infectious diseases · 2020Article
- A qualitative study of perceived barriers to hepatitis C care among people who did not attend appointments in the non-urban US South.Harm reduction journal · 2020Article
- A Call to Action: HCV Treatment of People Who Inject Drugs in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- UEG Week 2019 Poster Presentations.United European gastroenterology journal · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
This article proposes a strategy for primary care providers to begin treating patients with hepatitis C virus (HCV). We are motivated by the need to expand HCV treatment and by developments that have simplified treatment for most patients. This article presents 5 steps to achieving quality HCV treatment in the primary care setting: (1) accurate diagnosis via reflex testing; (2) risk stratification and identifying comorbidities via pretreatment evaluation; (3) simple, once-daily, pan-genotypic HCV treatment regimens; (4) minimized on-treatment monitoring: and (5) posttreatment monitoring and high-quality care for comorbidities such as cirrhosis and injection drug use. We provide indications for referral to specialists: notably children, patients with genotype 3 and cirrhosis, advanced liver or kidney disease, previous treatment failures, drug interactions with recommended regimens, and hepatitis B co-infection. Finally, potential barriers for providers are discussed, as well as further research findings and policy interventions that can promote HCV treatment in the primary care setting. We believe that a substantial portion of patients with HCV can be treated safely and effectively by nonspecialists and that the engagement of primary care providers is critical to efforts to end the HCV epidemic.
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Registered trials
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