Evidence map›Paper›PMID 29983146›Full record

ReviewInterventional cardiology clinics2018

Computed Tomography Fractional Flow Reserve to Guide Coronary Angiography and Intervention.

Roshin C Mathew, Matthew Gottbrecht, Michael Salerno

Abstract readReview
In one paragraph

Review in Interventional cardiology clinics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roshin C MathewDepartment of Medicine, University of Virginia Health System, University of Virginia, 131 Hospital Drive, Suite 1031, Charlottesville, VA 22904, USA.
Matthew GottbrechtDepartment of Medicine, University of Virginia Health System, University of Virginia, 131 Hospital Drive, Suite 1031, Charlottesville, VA 22904, USA.
Michael SalernoDepartment of Medicine, University of Virginia Health System, University of Virginia, 131 Hospital Drive, Suite 1031, Charlottesville, VA 22904, USA; Department of Radiology and Medical Imaging, The Cardiovascular Imaging Center, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA 22908, USA; Department of Biomedical Engineering, University of Virginia Health System, 415 Lane Road, Room 2010, Charlottesville, VA 22908, USA; Cardiovascular Division, University of Virginia Health System, 1215 Lee Street, PO Box 800158, Charlottesville, VA 22908, USA. Electronic address: ms5pc@virginia.edu.

Funding

Training in Cardiovascular Imaging ResearchT32EB003841 · NIBIB · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Jonathan R Lindner · 2004 to 2026
$4.4M
High-Resolution Whole Heart Quantitative CMR Perfusion Imaging in Ischemic Heart DiseaseR01HL131919 · NHLBI · UNIVERSITY OF VIRGINIA · PI ENNIS, DANIEL B · 2017 to 2021
$3.5M
NHLBI NIH HHS R01 HL131919NIBIB NIH HHS T32 EB003841
6 · The paper itself

Abstract

Computed tomography angiography (CTA) has played a significant role in evaluation of coronary artery disease in the last decade and has demonstrated high sensitivity and negative predictive values. However, the positive predictive value as compared with invasive fractional flow reserve (FFR) is limited. CT-FFR has emerged as a disruptive noninvasive technology with higher specificity and diagnostic accuracy for detection of hemodynamically significant coronary lesions as compared with invasive FFR than conventional coronary CTA. CT-FFR has been shown to be cost-effective as a gate-keeper to invasive coronary angiography and has the potential to limit unnecessary invasive angiography studies.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseCoronary VesselsEpidemiologic MethodsFractional Flow Reserve, MyocardialHumansPercutaneous Coronary InterventionCoronary artery diseaseCoronary computed tomography angiography (CTA)CT-FFRFractional flow reserve (FFR)

Identifiers

PMID29983146
PMCPMC6553476

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.