Evidence map›Paper›PMID 29982969›Full record

ArticleClinical oral investigations2019

Intratubular decontamination ability and physicochemical properties of calcium hydroxide pastes.

Thais Cristina Pereira, Layla Reginna da Silva Munhoz Vasconcelos, Márcia Sirlene Zardin Graeff, Maria Cristina Marcucci Ribeiro, Marco Antonio Hungaro Duarte, Flaviana Bombarda de Andrade

Abstract read
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In one paragraph

Article in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  3. The Clinical Effectiveness of Calcium Hydroxide in Root Canal Disinfection of Primary Teeth: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Pooled it
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  8. [Antibacterial properties, biocompatibility, and clinical selection strategies of root canal filling materials for primary teeth].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
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  20. Biocompatibility and Antibacterial Action ofMaterials (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Thais Cristina PereiraDepartment of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, 9-75, Alameda Dr.Octávio Pinheiro Brisola, Bauru, SP, 17012-901, Brazil. thais.cristina.pereira@usp.br.ORCID http://orcid.org/0000-0002-3390-9371
Layla Reginna da Silva Munhoz VasconcelosDepartment of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, 9-75, Alameda Dr.Octávio Pinheiro Brisola, Bauru, SP, 17012-901, Brazil.
Márcia Sirlene Zardin GraeffBauru School of Dentistry, University of São Paulo, 9-75, Alameda Dr.Octávio Pinheiro Brisola, Bauru, SP, 17012-901, Brazil.
Maria Cristina Marcucci RibeiroUniversity Bandeirante of São Paulo, 1245, Guilherme Giorgi Avenue, São Paulo, SP, Brazil.
Marco Antonio Hungaro DuarteDepartment of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, 9-75, Alameda Dr.Octávio Pinheiro Brisola, Bauru, SP, 17012-901, Brazil.
Flaviana Bombarda de AndradeDepartment of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, 9-75, Alameda Dr.Octávio Pinheiro Brisola, Bauru, SP, 17012-901, Brazil.
Universidade de São Paulo · BRHospital Bandeirantes · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2010/20186-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/26120-2
6 · The paper itself

Abstract

objectiveThis in vitro study compared the penetration, pH, calcium ion release, solubility, and intradentinal decontamination capacity of calcium hydroxide (CH) pastes with different vehicles and additives. MATERIALS AND

methodsInfected standard bovine dentine contaminated with Enterococcus faecalis were treated with propolis extract, chlorhexidine, and camphorated paramonochlorophenol (CPMC) loaded in CH paste for the bacterial viability evaluation made by confocal laser scanning microscopy (CLSM) and microbiological culture. Beside this, 50 acrylic teeth were filled with the previously mentioned pastes to evaluate the pH and calcium ion release (pHmeter and atomic absorption spectrophotometer at time intervals of 7, 15, and 30 days) and solubility (micro-computed tomographic imaging before and after 15 days).

resultsAfter treatment, all samples decreased intra-dentinal contamination, specially, the CH paste with CPMC. There was no statistically significant difference between the groups when evaluating the intra-canal paste penetration. In the pH measurements, CH with distilled water showed the smallest pH values. Regardless the solubility percentage of the pastes, the paste of CH + PG presented the highest values.

conclusionThe vehicles and additives tested may increase CH antimicrobial effect, but with small differences. In general, all CH pastes tested here were effective in reducing Enterococcus faecalis and were similar in the penetration, pH, calcium ion release, and solubility of calcium hydroxide when compared to distilled water. CLINICAL RELEVANCE: The use of calcium hydroxide pastes as intracanal medication with an aqueous or viscous vehicle, as propylene glycol, can be useful, since all formulations of the tested pastes resulted in great bacterial reduction inside root canals.

Indexed as

DecontaminationAnimalsCalcium HydroxideCattleChlorhexidineChlorophenolsDentinEnterococcus faecalisPropolisRoot Canal Irrigants4-chlorophenolCalcium HydroxideChlorhexidineChlorophenolsPropolisRoot Canal IrrigantsCalcium hydroxideCamphor paramonochlorophenolChlorhexidineEnterococcus faecalisMicroscopyPropolis

Identifiers

PMID29982969
OpenAlexW2816775025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.