Evidence map›Paper›PMID 29982846›Full record

ReviewHistochemistry and cell biology2018

Phospholipids and inositol phosphates linked to the epigenome.

Lívia Uličná, Darina Paprčková, Veronika Fáberová, Pavel Hozák

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histochemistry and cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Biology · 2026
    Article
  2. Review
  3. Article
  4. In focus in HCB.Histochemistry and cell biology · 2020
    Article
  5. Article
  6. Review
  7. Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions.International journal of molecular sciences · 2019
    Review
  8. In focus in HCB.Histochemistry and cell biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Lívia UličnáDepartment of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20, Prague, Czech Republic.
Darina PaprčkováDepartment of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20, Prague, Czech Republic.
Veronika FáberováDepartment of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20, Prague, Czech Republic.
Pavel HozákDepartment of Biology of the Cell Nucleus, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 142 20, Prague, Czech Republic. hozak@img.cas.cz.ORCID http://orcid.org/0000-0003-1901-1394
Czech Academy of Sciences · CZ

Funding

Akademie Věd České Republiky JSPS-18-18European Regional Development Fund CZ.02.1.01/0.0/0.0/16_013/0001775European Regional Development Fund CZ.1.05/1.1.00/02.0109Grantová Agentura České Republiky 15-08738SGrantová Agentura České Republiky 16-03346SGrantová Agentura České Republiky 17-09103SInstitutional Research Concept of the Institute of Molecular Genetics RVO: 68378050MEYS CR LM2015062 Czech-BioImaging
6 · The paper itself

Abstract

Even though the majority of knowledge about phospholipids comes from their cytoplasmic functions, in the last decade, it has been shown that nuclear phospholipids and their building blocks, inositol phosphates, have many important roles in the cell nucleus. There are clear connections of phospholipids with the regulation of gene expression and chromatin biology, however, this review focuses on less known functions of nuclear phospholipids in connection with the epigenome regulation. In particular, we highlight the roles of nuclear phospholipids and inositol phosphates that involve histone modifications, such as acetylation or methylation, tightly connected with the cell physiology. This demonstrates the importance of nuclear phospholipids in the regulation of cellular processes, and should encourage further research of nuclear phospholipids and inositol phosphates.

Indexed as

Epigenesis, GeneticAnimalsChromatinGene Expression RegulationHumansInositol PhosphatesMolecular StructurePhospholipidsChromatinInositol PhosphatesPhospholipidsAcetylationInositol phosphateMethylationPhosphoinositidePhospholipids

Identifiers

PMID29982846
OpenAlexW2842105762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.