SynthesisJournal of pediatric psychology2019
Family Functioning and Medical Adherence Across Children and Adolescents With Chronic Health Conditions: A Meta-Analysis.
Synthesis in Journal of pediatric psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Using Real Time Mobile Health Approaches to Understand and Promote Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia
Adolescent Surgery Roadmap Feasibility and Acceptability Study
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adherence to Oral Chemotherapy in Acute Lymphoblastic Leukemia during Maintenance Therapy in Children, Adolescents, and Young Adults: A Systematic Review.Current oncology (Toronto, Ont.) · 2023Pooled it
- Check the Impact of Mobile Health on Medication Adherence in Adolescents with Leukemia.Asian Pacific journal of cancer prevention : APJCP · 2025Trial
- A randomized clinical trial to support adherence regimens in children with epilepsy: Examining potential mechanisms of change.Epilepsy & behavior : E&B · 2023Trial
- Review
- [Status and influencing factors of transition preparation in adolescents with thalassemia major].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Profiles and Predictors of Family Functioning in Families of Children with Mowat-Wilson Syndrome: A Cross-Sectional Survey.Healthcare (Basel, Switzerland) · 2026Article
- Exploring Strategies for a Digital Tool to Support Medication Adherence Among Adolescents and Young Adults Undergoing Hematopoietic Stem Cell Transplant and Their Care Partners: Qualitative Formative Study.JMIR formative research · 2026Article
- Toward Better Conversations: Assessing Caregiver-Child Communication in Pediatric Oncology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Health-related quality of life among families of children with severe bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Understanding factors related to application of traditional Chinese medicine tuina for congenital muscular torticollis in children: a qualitative study based on traditional Chinese medicine tuina practitioners.BMC complementary medicine and therapies · 2026Article
- Process of empowerment in mothers of children with very-early-onset inflammatory bowel disease: a qualitative study.Intestinal research · 2026Article
- Relationships between family functioning and HIV/AIDS-related preventive behaviors among young students with sexual experience.Frontiers in public health · 2026Article
- Narrative medicine approach for assessing the emotional experience of children and adolescents treated with daily rhGH and their caregivers.Frontiers in endocrinology · 2026Article
- Delivering Care Consistent With the Psychosocial Standards-Provider Report: Implementing the Standards Together-Engaging Parents and Providers in Psychosocial Care (iSTEPPP) Study.Pediatric blood & cancer · 2025Article
- Adherence to daily electronic symptom screening in pediatric cancer: associations with time, location and pain.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Family partnerships to support equity and cultural humility in pediatric intervention research.Journal of pediatric psychology · 2025Article
- Reinforcement Learning on Dyads to Enhance Medication Adherence.Artificial intelligence in medicine. Conference on Artificial Intelligence in Medicine (2005- ) · 2025Article
- Article
- Family functioning in adolescents and young adults with differences of sex development.Journal of pediatric psychology · 2025Article
- Context Factors Associated with Medication Adherence Among Thai Adolescents with Major Depressive Disorder.Patient preference and adherence · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Objectives: A meta-analysis examined family functioning and medical adherence in children and adolescents with chronic health conditions. Family functioning was evaluated at the level of the family unit, as well as parent-child interactions. Methods: We conducted literature searches using PubMed, PsycINFO, SCOPUS, Web of Science, and Cochrane. After reviewing 764 articles, 62 studies met eligibility criteria. Pearson's r correlations were the effect size of interest. We conducted both omnibus and domain-specific (e.g., family conflict, cohesion) meta-analyses. Meta-regressions examined whether relevant covariates related to the magnitude of the effect. Results: The omnibus meta-analysis showed that family functioning was significantly related to medical adherence across a variety of pediatric chronic health conditions. Lower family conflict, greater family cohesion, greater family flexibility, more positive communication, and better family problem-solving were each associated with better adherence. There were no significant differences in the magnitude of the omnibus effect based on child age, measurement features (subjective vs. objective or bioassay adherence; family unit vs. parent-child interactions), or study quality. Conclusions: Consistent with social-ecological frameworks, findings supported links between family functioning and medical adherence. This study highlights several limitations of the extant research, including absence of a guiding theoretical framework and several methodological weaknesses. We offer clinical and research recommendations for enhancing scientific understanding and promotion of adherence within the family context.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.