Evidence map›Paper›PMID 29982512›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA2018

A systematic assessment of the availability and clinical drug information coverage of machine-readable clinical drug data sources for building knowledge translation products.

Catherine Anne Grandy, Jennifer R Donnan, Justin T Peddle, Kristen Romme, Satpyul Kim, John-Michael Gamble

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Catherine Anne GrandySchool of Pharmacy, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Jennifer R DonnanSchool of Pharmacy, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Justin T PeddleSchool of Pharmacy, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Kristen RommeHealth Sciences Library, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Satpyul KimSchool of Pharmacy, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
John-Michael GambleSchool of Pharmacy, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.

Funding

CIHR
6 · The paper itself

Abstract

Objective: To identify and describe clinical drug data sources that have the potential to serve as a repository of information for developing drug knowledge translation products. Methods: Two reviewers independently screened citations from PubMed and Embase, websites from the web search engine Google, and references from selected journals. Publicly licensed or non-proprietary data sources containing clinical drug information accessible in a machine-readable format were eligible. Data sources were assessed for their coverage across 18 pre-specified domains and 74 elements of clinical drug information. Results: Of the 3369 unique citations or webpages screened, 44 drug information data sources were identified. Of these, 22 data sources met the study inclusion criteria. There was a mean of 4.5 (SD = 5.19) domains covered by each source and a mean of 10.9 (SD = 18) elements covered by each source. None of the data sources covered all domains and eight elements were not addressed by any source. All of the data sources identified by the study are government or academic databases. Conclusion: Our study demonstrated the availability of machine-readable clinical drug data that could help facilitate the creation of novel drug knowledge translation products. However, we identified clinical content gaps in the available non-proprietary drug information sources. Further evaluation of the quality of each data source would be necessary prior to incorporating these sources into any knowledge translation products intended for clinical use.

Indexed as

Databases, FactualDrug TherapyPharmaceutical PreparationsDrug InteractionsDrug-Related Side Effects and Adverse ReactionsHumansTranslational Research, BiomedicalPharmaceutical Preparations

Identifiers

PMID29982512
PMCPMC6118868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.