Evidence map›Paper›PMID 29982511›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2018

Identifying surgical site infections in electronic health data using predictive models.

Robert W Grundmeier, Rui Xiao, Rachael K Ross, Mark J Ramos, Dean J Karavite, Jeremy J Michel, Jeffrey S Gerber, Susan E Coffin

Open access · bronzeAbstract readValidation Study
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Robert W GrundmeierDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Rui XiaoDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Rachael K RossCenter for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.
Mark J RamosDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Dean J KaraviteDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Jeremy J MichelDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Jeffrey S GerberDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Susan E CoffinDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Electronic Surveillance for Wound Infections after Ambulatory Pediatric SurgeryR01HS020921 · AHRQ · CHILDREN'S HOSP OF PHILADELPHIA · PI COFFIN, SUSAN MD · 2011 to 2015
$2.5M
AHRQ HHS R01 HS020921
6 · The paper itself

Abstract

Objective: The objective was to prospectively derive and validate a prediction rule for detecting cases warranting investigation for surgical site infections (SSI) after ambulatory surgery. Methods: We analysed electronic health record (EHR) data for children who underwent ambulatory surgery at one of 4 ambulatory surgical facilities. Using regularized logistic regression and random forests, we derived SSI prediction rules using 30 months of data (derivation set) and evaluated performance with data from the subsequent 10 months (validation set). Models were developed both with and without data extracted from free text. We also evaluated the presence of an antibiotic prescription within 60 days after surgery as an independent indicator of SSI evidence. Our goal was to exceed 80% sensitivity and 10% positive predictive value (PPV). Results: We identified 234 surgeries with evidence of SSI among the 7910 surgeries available for analysis. We derived and validated an optimal prediction rule that included free text data using a random forest model (sensitivity = 0.9, PPV = 0.28). Presence of an antibiotic prescription had poor sensitivity (0.65) when applied to the derivation data but performed better when applied to the validation data (sensitivity = 0.84, PPV = 0.28). Conclusions: EHR data can facilitate SSI surveillance with adequate sensitivity and PPV.

Indexed as

Electronic Health RecordsModels, StatisticalSurgical Wound InfectionAmbulatory Surgical ProceduresChildHumansLogistic ModelsProspective StudiesRisk AssessmentRisk Factors

Identifiers

PMID29982511
PMCPMC7646895
OpenAlexW2810531395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.