Evidence map›Paper›PMID 29982487›Full record

Observational studyThe Journal of infectious diseases2018

Chronic Kidney Disease Risk in African and Caribbean Populations With HIV.

Sophie Jose, Lisa Hamzah, Rachael Jones, Debbie Williams, Alan Winston, Fiona Burns, Andrew N Phillips, Caroline A Sabin, Frank A Post, UK CHIC Study

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in The Journal of infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Kidney international reports · 2026
    Article
  3. Article
  4. Progression of HIV-1 CKDs: Viral Load VersusKidney international reports · 2025
    Article
  5. Article
  6. Genetic Variants ofKidney international reports · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sophie JoseInstitute for Global Health, University College London.
Lisa HamzahDepartment of Sexual Health, King's College Hospital NHS Foundation Trust, London.
Rachael JonesDepartment of Sexual Health, Chelsea and Westminster Hospital NHS Foundation Trust, London.
Debbie WilliamsDepartment of Sexual Health, Brighton and Sussex University Hospitals NHS Trust.
Alan WinstonDivision of Infectious Diseases, Department of Medicine, Imperial College London, United Kingdom.
Fiona BurnsInstitute for Global Health, University College London.
Andrew N PhillipsInstitute for Global Health, University College London.
Caroline A SabinInstitute for Global Health, University College London.
Frank A PostDepartment of Sexual Health, King's College Hospital NHS Foundation Trust, London.
UK CHIC Study
University College London · GBKing's College Hospital NHS Foundation Trust · GBChelsea and Westminster Hospital NHS Foundation Trust · GBImperial College London · GBUniversity Hospitals Sussex NHS Foundation Trust · GB

Funding

Medical Research Council G0000199Medical Research Council G0600337Medical Research Council G0900274Medical Research Council MC_U122886351Medical Research Council MC_UU_12023/15Medical Research Council MR/M004236/1
6 · The paper itself

Abstract

We conducted an observational cohort study of end-stage kidney disease (ESKD) in >7000 African and Caribbean people with HIV in the UK. Using Poisson regression and East Africans as the reference group, the adjusted incidence rate ratio (95% confidence interval) of ESKD was 3.14 (1.26-7.84) in Southern Africans, 6.35 (2.53-15.96) in West Africans, and 5.26 (1.91-14.43) in Caribbeans. Higher CD4 cell count and suppressed HIV replication were associated with reduced risk of ESKD. The risk of ESKD varied among HIV-positive people of African heritage, with the highest rates observed in those of West African descent.

Indexed as

HIV InfectionsRenal Insufficiency, ChronicAdultAfrica, SouthernAfrica, WesternBlack PeopleCaribbean RegionFemaleHumansMaleMiddle AgedUnited Kingdom

Identifiers

PMID29982487
PMCPMC6195659
OpenAlexW2884072171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.