ArticleGenome biology and evolution2018
Multiple Rounds of Artificial Selection Promote Microbe Secondary Domestication-The Case of Cachaça Yeasts.
Article in Genome biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed.
- Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics.Nature communications · 2026Article
- Horizontal Transfer and Recombination Fuel Ty4 Retrotransposon Evolution in Saccharomyces.Genome biology and evolution · 2025Article
- Copper-based grape pest management has impacted wine aroma.Scientific reports · 2024Article
- Ancient and recent origins of shared polymorphisms in yeast.Nature ecology & evolution · 2024Article
- Selected cachaça yeast strains share a genomic profile related to traits relevant to industrial fermentation processes.Applied and environmental microbiology · 2024Article
- The potential for Scotch Malt Whisky flavour diversification by yeast.FEMS yeast research · 2024Review
- Improved Sugarcane-Based Fermentation Processes by an Industrial Fuel-Ethanol Yeast Strain.Journal of fungi (Basel, Switzerland) · 2023Article
- Yeast population dynamics in Brazilian bioethanol production.G3 (Bethesda, Md.) · 2023Article
- Phylogenomics of aiScience · 2022Article
- Genomic Adaptations ofMicroorganisms · 2022Review
- Insights on life cycle and cell identity regulatory circuits for unlocking genetic improvement in Zygosaccharomyces and Kluyveromyces yeasts.FEMS yeast research · 2021Article
- Complete genome sequence and analysis of a Saccharomyces cerevisiae strain used for sugarcane spirit production.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Comparative Genomics Supports That Brazilian BioethanolFrontiers in microbiology · 2021Article
- Revisiting the Taxonomic Synonyms and Populations ofMicroorganisms · 2020Article
- Vitamin requirements and biosynthesis in Saccharomyces cerevisiae.Yeast (Chichester, England) · 2020Review
- Evolution of Ty1 copy number control in yeast by horizontal transfer and recombination.PLoS genetics · 2020Article
- Fermentation innovation through complex hybridization of wild and domesticated yeasts.Nature ecology & evolution · 2019Article
- Quantitative Trait Nucleotides Impacting the Technological Performances of IndustrialFrontiers in genetics · 2019Article
- Controlled Reduction of Genomic Heterozygosity in an Industrial Yeast Strain Reveals Wide Cryptic Phenotypic Variation.Frontiers in genetics · 2019Article
- A Quasi-Domesticate Relic Hybrid Population ofFrontiers in genetics · 2019Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The study of microbe domestication has witnessed major advances that contribute to a better understanding of the emergence of artificially selected phenotypes and set the foundations of their rational improvement for biotechnology. Several features make Saccharomyces cerevisiae an ideal model for such a study, notably the availability of a catalogue of signatures of artificial selection and the extensive knowledge available on its biological processes. Here, we investigate with population and comparative genomics a set of strains used for cachaça fermentation, a Brazilian beverage based on the fermentation of sugar cane juice. We ask if the selective pressures posed by this fermentation have given rise to a domesticated lineage distinct from the ones already known, like wine, beer, bread, and sake yeasts. Our results show that cachaça yeasts derive from wine yeasts that have undergone an additional round of domestication, which we define as secondary domestication. As a consequence, cachaça strains combine features of wine yeasts, such as the presence of genes relevant for wine fermentation and advantageous gene inactivations, with features of beer yeasts like resistance to the effects of inhibitory compounds present in molasses. For other markers like those related to sulfite resistance and biotin metabolism our analyses revealed distributions more complex than previously reported that support the secondary domestication hypothesis. We propose a multilayered microbe domestication model encompassing not only transitions from wild to primarily domesticated populations, as in the case of wine yeasts, but also secondary domestications like those of cachaça yeasts.
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