ArticleAmerican journal of epidemiology2018
Targeted Estimation of the Relationship Between Childhood Adversity and Fluid Intelligence in a US Population Sample of Adolescents.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06119503 (Peer Delivered Episodic Future Thinking to Improve MOUD Treatment Engagement Among Returning Citizens - A Randomized Controlled Trial), which is not on this map. Cited by 17 papers.
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Peer Delivered Episodic Future Thinking to Improve MOUD Treatment Engagement Among Returning Citizens - A Randomized Controlled Trial
Who cites it
17 citing papers in PubMed.
- Pathways from chronic stress to cognitive decline: A multi-cohort mediation analysis of inflammation and immune-related gene expression.Brain, behavior, & immunity - health · 2026Article
- Alcohol amount, drinking patterns, and gastric cancer risk: a nationwide study using targeted maximum likelihood estimation.European journal of epidemiology · 2026Article
- Optimal brain development is context-dependent: How socioeconomic status moderates brain-behavior relationships in cognitive and academic development.Neuroscience and biobehavioral reviews · 2026Review
- Cognitive ability following exposure to parental mental disorders and other childhood adversities: a population-based cohort study of Danish males in late adolescence.European journal of pediatrics · 2026Article
- The moderating role of parent-child interaction in the relationship between maltreatment and psychological well-being among preschool children.Frontiers in psychology · 2024Article
- Threat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents.Developmental science · 2023Article
- Mapping of machine learning approaches for description, prediction, and causal inference in the social and health sciences.Science advances · 2022Review
- Evaluating the robustness of targeted maximum likelihood estimators via realistic simulations in nutrition intervention trials.Statistics in medicine · 2022Article
- A scoping review on the use of machine learning in research on social determinants of health: Trends and research prospects.SSM - population health · 2021Article
- Extracurricular Activities, Screen Media Activity, and Sleep May Be Modifiable Factors Related to Children's Cognitive Functioning: Evidence From the ABCD StudyChild development · 2021Article
- Rethinking Concepts and Categories for Understanding the Neurodevelopmental Effects of Childhood Adversity.Perspectives on psychological science : a journal of the Association for Psychological Science · 2021Article
- Comparison of three models of adverse childhood experiences: Associations with child and adolescent internalizing and externalizing symptoms.Journal of abnormal psychology · 2021Article
- Early life stress and development: potential mechanisms for adverse outcomes.Journal of neurodevelopmental disorders · 2020Review
- Earlier age at menarche as a transdiagnostic mechanism linking childhood trauma with multiple forms of psychopathology in adolescent girls.Psychological medicine · 2020Article
- Associations between cortical thickness and reasoning differ by socioeconomic status in development.Developmental cognitive neuroscience · 2019Article
- Article
- Early-life threat and deprivation: Are children similarly affected by exposure to each?Child developmentArticle
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Authors and funding
6 authors.
Funding
Abstract
Many studies have shown inverse associations between childhood adversity and intelligence, although most are based on small clinical samples and fail to account for the effects of multiple co-occurring adversities. Using data from the 2001-2004 National Comorbidity Survey Adolescent Supplement, a cross-sectional US population study of adolescents aged 13-18 years (n = 10,073), we examined the associations between 11 childhood adversities and intelligence, using targeted maximum likelihood estimation. Targeted maximum likelihood estimation incorporates machine learning to identify the relationships between exposures and outcomes without overfitting, including interactions and nonlinearity. The nonverbal score from the Kaufman Brief Intelligence Test was used as a standardized measure of fluid reasoning. Childhood adversities were grouped into deprivation and threat types based on recent conceptual models. Adjusted marginal mean differences compared the mean intelligence score if all adolescents experienced each adversity to the mean in the absence of the adversity. The largest associations were observed for deprivation-type experiences, including poverty and low parental education, which were related to reduced intelligence. Although lower in magnitude, threat events related to intelligence included physical abuse and witnessing domestic violence. Violence prevention and poverty-reduction measures would likely improve childhood cognitive outcomes.
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