ArticleNutrition (Burbank, Los Angeles County, Calif.)2018
Association of proinflammatory diet with low-grade inflammation: results from the Moli-sani study.
Article in Nutrition (Burbank, Los Angeles County, Calif.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Dietary Patterns Associated With Anti-inflammatory Effects: An Umbrella Review of Systematic Reviews and Meta-analyses.Nutrition reviews · 2026Pooled it
- Impact of dietary inflammatory index on gestational diabetes mellitus in normal and overweight women: a systematic review and meta-analysis of observational studies.Asia Pacific journal of clinical nutrition · 2024Pooled it
- Dietary Inflammatory Index in relation to Type 2 Diabetes: A Meta-Analysis.International journal of clinical practice · 2022Pooled it
- Dietary inflammatory index potentially increases blood pressure and markers of glucose homeostasis among adults: findings from an updated systematic review and meta-analysis.Public health nutrition · 2020Pooled it
- Dietary inflammatory index and risk of gynecological cancers: a systematic review and meta-analysis of observational studies.Journal of gynecologic oncology · 2019Pooled it
- Adherence to a Mediterranean Diet for 6 Months Improves the Dietary Inflammatory Index in a Western Population: Results from the MedLey Study.Nutrients · 2023Trial
- Review
- The association between pro-inflammatory diet and incidence of hypertension: a prospective cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- MIND-NL diet adherence moderates the relation of low-grade systemic inflammation with neuroinflammatory metabolites and cognitive functioning: an exploratory cross-sectional study in older adults.Journal of neuroinflammation · 2026Article
- Dietary inflammatory potential, systemic inflammation, and cognitive function in healthy adults in Saudi Arabia.Frontiers in nutrition · 2026Article
- The association between a pro-inflammatory diet and brain age in middle-aged and older adults.European journal of epidemiology · 2026Article
- Associations between the dietary inflammatory index, body mass index, and waist-to-height ratio and diagnosed and undiagnosed diabetes mellitus in adults in Guangxi, China.BMC public health · 2025Article
- Dietary Inflammatory Potential and Sociodemographic Correlates Among Adults in Saudi Arabia: A Cross-Sectional Study.Nutrients · 2025Article
- Exploring the Anti-Inflammatory Potential of a Mediterranean-Style Ketogenic Diet in Women with Lipedema.Nutrients · 2025Article
- Association Between the Dietary Inflammatory Index and Depression in Mid-Pregnancy: Mediating Effect of Sleep Quality.Nutrients · 2025Article
- Relationship between dietary inflammatory index and chronic diseases in older U.S. Adults: NHANES 1999-2018.BMC public health · 2025Article
- The Dietary Inflammatory Index (DII) and COPD: A Cross-Sectional Study from the NHANES.International journal of chronic obstructive pulmonary disease · 2025Article
- Association of dietary quality and dietary inflammatory potential with inflammatory markers: evidence from the national health and nutrition examination survey 2009-2018.Frontiers in immunology · 2025Article
- Cross-talk of inflammation and cellular senescence: a new insight into the occurrence and progression of osteoarthritis.Bone research · 2024Review
- Trends in Children's Dietary Inflammatory Index and association with prediabetes in U.S. adolescents.Nutrition & diabetes · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectivesThe association between diet and inflammation is well documented. Yet, no evidence exists on the relationship between the inflammatory potential of the diet and low-grade inflammation (LGI) as measured by a composite score of plasma and cellular biomarkers. The aim of this study was to assess the association between the Dietary Inflammatory Index (DII
methodsCross-sectional analyses were conducted on data from 20 823 adults (age ≥35 y; 48% male) without acute inflammation, who were recruited within the general population of the Moli-sani study from 2005 to 2010. LGI was measured by using a composite score (INFLA-score) including platelet and leukocyte counts, the granulocyte to lymphocyte ratio, and C-reactive protein. DII scores were computed based on dietary intake assessed by the EPIC food frequency questionnaire. Multivariable linear regression models were fit to produce adjusted regression coefficients and 95% confidence intervals (CIs).
resultsHigher DII scores were associated with increased LGI (β = 0.131; 95% CI, 0.089-0.174 for the highest versus lowest quintile of DII) after adjusting for age, sex, lifestyle, prevalence of chronic diseases, and health conditions. A higher DII score also was positively associated with each single biomarker of inflammation included in the INFLA-score, unhealthy behaviors (smoking, sedentary lifestyle), and insulin.
conclusionsHigher DII scores, indicating greater inflammatory potential of the diet, were directly associated with LGI, as measured by a composite score of plasma and cellular biomarkers of inflammation. These findings are consistent with the contributing role of diet-mediated inflammation in increasing risk for inflammation-related chronic diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.