Evidence map›Paper›PMID 29981699›Full record

ArticleVeterinary microbiology2018

Porcine epidemic diarrhea virus (PEDV) introduction into a naive Dutch pig population in 2014.

J C F M Dortmans, W Li, P J van der Wolf, G J Buter, P J M Franssen, G van Schaik, M Houben, B J Bosch

Open access · greenAbstract read
In one paragraph

Article in Veterinary microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  10. Gossypol Broadly Inhibits Coronaviruses by Targeting RNA-Dependent RNA Polymerases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  11. Review
  12. Proximity to livestock farms and COVID-19 in the Netherlands, 2020-2021.International journal of hygiene and environmental health · 2022
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

J C F M DortmansGD Animal Health, 7400 AA, Deventer, The Netherlands. Electronic address: j.dortmans@gddiergezondheid.nl.
W LiVirology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
P J van der WolfGD Animal Health, 7400 AA, Deventer, The Netherlands; Present address: IDT-Biologika Benelux, Breda, The Netherlands.
G J ButerGD Animal Health, 7400 AA, Deventer, The Netherlands.
P J M FranssenGD Animal Health, 7400 AA, Deventer, The Netherlands.
G van SchaikGD Animal Health, 7400 AA, Deventer, The Netherlands; Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
M HoubenGD Animal Health, 7400 AA, Deventer, The Netherlands.
B J BoschVirology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
De Gezondheidsdienst voor Dieren · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV) is the highly contagious, causative agent of an economically important acute enteric disease in pigs of all ages. The disease is characterized by diarrhea and dehydration causing mortality and growth retardation. In the last few decades, only classical PEDV was reported sporadically in Europe, but in 2014 outbreaks of PEDV were described in Germany. Phylogenetic analysis showed a very high nucleotide similarity with a variant of PEDV that was isolated in the US in January 2014. The epidemiological situation of PEDV infections in the Netherlands in 2014 was unknown and a seroprevalence study in swine was performed. In total, 838 blood samples from sows from 267 farms and 101 samples from wild boars were collected from May till November 2014 and tested for antibodies against PEDV by ELISA. The apparent herd prevalence of 0.75% suggests that PEDV was not circulating on a large scale in the Netherlands at this time. However, in November 2014 a clinical outbreak of PEDV was diagnosed in a fattener farm by PCR testing. This was the first confirmed PEDV outbreak since the early nineties. Sequence analyses showed that the viruses isolated in 2014 and 2015 in the Netherlands cluster with recently found European G1b strains. This suggests a one event introduction of PEDV G1b strains in Europe in 2014, which made the Netherlands and other European countries endemic for this type of strains since then.

Indexed as

PhylogenyAnimalsCoronavirus InfectionsFarmsNetherlandsPolymerase Chain ReactionPorcine epidemic diarrhea virusRNA, ViralSwineRNA, ViralELISAEpidemiologyOutbreakPorcine epidemic diarrhea virus (PEDV)Sequence analysisSerological survey

Identifiers

PMID29981699
PMCPMC7117506
OpenAlexW2803480909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.