Evidence map›Paper›PMID 29981692›Full record

ReviewDevelopmental biology2018

Migration and diversification of the vagal neural crest.

Erica J Hutchins, Ezgi Kunttas, Michael L Piacentino, Aubrey G A Howard, Marianne E Bronner, Rosa A Uribe

Abstract readReview
In one paragraph

Review in Developmental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock-ins.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. BMP signaling pathway member expression is enriched in enteric neural progenitors and required for zebrafish enteric nervous system development.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  7. Lineage labeling with zebrafishbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Review
  10. Innervation of adipocytes is limited in mouse perivascular adipose tissue.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Endothelin signaling in development.Development (Cambridge, England) · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erica J HutchinsDivision of Biology and Biological Engineering, Caltech, 1200 E. California Blvd., Pasadena, CA 91125, United States.
Ezgi KunttasDivision of Biology and Biological Engineering, Caltech, 1200 E. California Blvd., Pasadena, CA 91125, United States.
Michael L PiacentinoDivision of Biology and Biological Engineering, Caltech, 1200 E. California Blvd., Pasadena, CA 91125, United States.
Aubrey G A HowardBiosciences Department, Rice University, 6100 Main Street, Houston, TX 77005, United States.
Marianne E BronnerDivision of Biology and Biological Engineering, Caltech, 1200 E. California Blvd., Pasadena, CA 91125, United States.
Rosa A UribeBiosciences Department, Rice University, 6100 Main Street, Houston, TX 77005, United States. Electronic address: rosa.uribe@rice.edu.

Funding

Transcriptional Casualty in Embryonic Morphogenesis: from the Specifications GRNP01HD037105 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BRONNER, MARIANNE · 1999 to 2018
$27.1M
Gene Regulatory Network Controlling Premigratory Cranial vs Trunk Neural CrestR01DE024157 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BRONNER, MARIANNE · 2014 to 2025
$4.0M
Clonal analysis of the cranial neural crestR01DE027568 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BRONNER, MARIANNE · 2018 to 2022
$2.2M
Functional analysis of draxin in cranial neural crest emigrationF32DE026355 · NIDCR · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HUTCHINS, ERICA · 2016 to 2018
$181k
Role of JAK/Stat signaling during zebrafish neural crest delamination and migrationF32HD087026 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KUNTTAS-TATLI, EZGI · 2016 to 2018
$179k
Determining the position and role of MafB and Krox20 in the cardiac neural crest cell gene regulatory programF32HD088022 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PIACENTINO, MICHAEL LOUIS · 2016 to 2018
$170k
NICHD NIH HHS F32 HD087026NICHD NIH HHS F32 HD088022NICHD NIH HHS L40 HD096443NICHD NIH HHS P01 HD037105NIDCR NIH HHS F32 DE026355NIDCR NIH HHS L40 DE028128NIDCR NIH HHS R01 DE024157NIDCR NIH HHS R01 DE027568
6 · The paper itself

Abstract

Arising within the neural tube between the cranial and trunk regions of the body axis, the vagal neural crest shares interesting similarities in its migratory routes and derivatives with other neural crest populations. However, the vagal neural crest is also unique in its ability to contribute to diverse organs including the heart and enteric nervous system. This review highlights the migratory routes of the vagal neural crest and compares them across multiple vertebrates. We also summarize recent advances in understanding vagal neural crest ontogeny and discuss the contribution of this important neural crest population to the cardiovascular system and endoderm-derived organs, including the thymus, lungs and pancreas.

Indexed as

AnimalsBiological EvolutionBody PatterningCell DifferentiationCell MovementEnteric Nervous SystemGangliaHeartHumansLungNeural CrestNeural TubeNeurogenesisPancreasThymus GlandTorsoCardiacLungPancreasThymusVagal neural crest

Identifiers

PMID29981692
PMCPMC6320731

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.