Evidence map›Paper›PMID 29981000›Full record

ArticleJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2019

CCR2 on Peripheral Blood CD14

Mike Veenstra, Desiree A Byrd, Matilde Inglese, Korhan Buyukturkoglu, Dionna W Williams, Lazar Fleysher, Ming Li, Lucio Gama, Rosiris León-Rivera, Tina M Calderon and 3 more

Abstract read
In one paragraph

Article in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. EcoHIV Infection Promotes Atherosclerosis Progression in LDLR-Deficient Mice.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Role of Monocyte/Macrophages in the Pathogenesis of NeuroHIV.Results and problems in cell differentiation · 2024
    Review
  15. Review
  16. Review
  17. Cerebrospinal fluid CD14Journal of neurovirology · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Mike VeenstraDepartment of Pathology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Desiree A ByrdDepartments of Neurology, and Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Matilde IngleseDepartments of Neurology, Neuroscience, and Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Korhan BuyukturkogluDepartments of Neurology, Neuroscience, and Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Dionna W WilliamsDepartment of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Lazar FleysherDepartment of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Ming LiDepartment of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Lucio GamaDepartment of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Rosiris León-RiveraDepartment of Pathology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Tina M CalderonDepartment of Pathology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.ORCID 0000-0001-9929-7120
Janice E ClementsDepartment of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Susan MorgelloDepartments of Neurology, Pathology, and Neuroscience, Icahn School of Medicine at Mount Sinai, 1468 Madison Ave, New York, NY, 10029, USA. susan.morgello@mssm.edu.
Joan W BermanDepartments of Pathology, and Microbiology and Immunology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA. joan.berman@einstein.yu.edu.
Icahn School of Medicine at Mount Sinai · USAlbert Einstein College of Medicine · USJohns Hopkins University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6M
Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Kathryn M. Anastos · 2017 to 2026
$28.3M
CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
The Manhattan HIV Brain BankU24MH100931 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MORGELLO, SUSAN · 2013 to 2023
$14.0M
Mechanisms of HAD:Role of CCL2 BBB & HIV InfectionR01MH075679 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER · 2006 to 2016
$4.0M
Macrophage Ontogeny and Polarization in HIV/SIV InfectionR01AI127142 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CLEMENTS, JANICE E, GAMA, LUCIO · 2016 to 2020
$3.8M
Novel SIV Model of HANDR01NS077869 · NINDS · JOHNS HOPKINS UNIVERSITY · PI CLEMENTS, JANICE E, MANKOWSKI, JOSEPH L · 2012 to 2016
$3.8M
Monocyte CNS HIV entry & neurodegeneration: Translational studies in the CART eraR01MH112391 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER, MORGELLO, SUSAN · 2017 to 2021
$3.7M
The Mount Sinai Institute for NeuroAIDS DisparitiesR25MH080663 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MORGELLO, SUSAN · 2007 to 2015
$2.1M
Role of cellular prion protein in the pathogenesis of NeuroAIDSR01MH090958 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER · 2011 to 2015
$1.9M
Clinical and Translational Science AwardTL1TR001072 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SHAMOON, HARRY · 2013 to 2017
$909k
Mechanisms of HIV Tat regulation of macrophage gene expression in neuroAIDSR21MH102113 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BERMAN, JOAN WEINBERGER · 2014 to 2015
$459k
NCATS NIH HHS TL1 TR001072NCATS NIH HHS UL1 TR002556NIAID NIH HHS P30 AI124414NIAID NIH HHS R01 AI127142NIGMS NIH HHS T32 GM007288NIMH NIH HHS R01 MH075679NIMH NIH HHS R01 MH090958NIMH NIH HHS R01 MH112391NIMH NIH HHS R21 MH102113NIMH NIH HHS R25 MH080663NIMH NIH HHS U24 MH100931NINDS NIH HHS R01 NS077869
6 · The paper itself

Abstract

HIV-associated neurocognitive disorders (HAND) occur in ~50% of HIV infected individuals despite combined antiretroviral therapy. Transmigration into the CNS of CD14

Indexed as

AdultAgedAIDS Dementia ComplexBiomarkersDNA, ViralFemaleGPI-Linked ProteinsHumansLipopolysaccharide ReceptorsMaleMiddle AgedMonocytesReceptors, CCR2Receptors, IgGBiomarkersCCR2 protein, humanCD14 protein, humanDNA, ViralFCGR3B protein, humanGPI-Linked ProteinsLipopolysaccharide ReceptorsReceptors, CCR2Receptors, IgGCCR2CD14+CD16+ MonocytesddPCRHANDHIVMRI/MRS

Identifiers

PMID29981000
PMCPMC6320730
OpenAlexW2847150115

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.