Evidence map›Paper›PMID 29980918›Full record

Observational studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2018

Superficial and deep retinal foveal avascular zone OCTA findings of non-infectious anterior and posterior uveitis.

Maria Waizel, Margarita G Todorova, Celine Terrada, Phuc LeHoang, Natalie Massamba, Bahram Bodaghi

Abstract readComparative StudyMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. The impact of macular edema on microvascular and metabolic alterations in retinitis pigmentosa.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. [Foveal avascular zone and OCT angiography. An overview of current knowledge].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2019
    Review
  10. Optical coherence tomography angiography (OCTA) as a new diagnostic tool in uveitis.Journal of ophthalmic inflammation and infection · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Maria WaizelDepartment of Ophthalmology, University Hospital Basel, Mittlere Strasse 91, CH-4031, Basel, Switzerland. maria.waizel@usb.ch.ORCID http://orcid.org/0000-0002-6588-4842
Margarita G TodorovaDepartment of Ophthalmology, University Hospital Basel, Mittlere Strasse 91, CH-4031, Basel, Switzerland.
Celine TerradaDHU Vision and Handicaps, Pierre and Marie Curie School of Medicine, Sorbonne Universités, Paris, France.
Phuc LeHoangDHU Vision and Handicaps, Pierre and Marie Curie School of Medicine, Sorbonne Universités, Paris, France.
Natalie MassambaDHU Vision and Handicaps, Pierre and Marie Curie School of Medicine, Sorbonne Universités, Paris, France.
Bahram BodaghiDHU Vision and Handicaps, Pierre and Marie Curie School of Medicine, Sorbonne Universités, Paris, France.
Sorbonne Université · FRInstitut de la Vision · FRUniversity of Basel · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung IZK0Z3_173498/1
6 · The paper itself

Abstract

purposeTo compare the superficial (FAZ-S) and deep foveal avascular zones (FAZ-D) of non-infectious anterior and posterior uveitis to healthy controls, using optical coherence tomography angiography (OCTA).

methodsOCTA was performed on 74 eyes: 34 eyes with non-infectious posterior uveitis (with (post+CME) and without macular edema (post-CME)), 11 eyes with non-infectious anterior uveitis (with (ant+CME) and without macular edema (ant-CME)), and the control group which included 29 healthy eyes.

resultsEyes suffering from non-infectious posterior uveitis presented with significantly larger FAZ-D when compared to healthy controls, both in the presence or in the absence of macular edema (p < 0.001). In the presence of macular edema, eyes presenting with anterior uveitis (ant+CME) also showed significantly larger FAZ-S (p = 0.03) and FAZ-D (p < 0.001), when compared to healthy controls. In the absence of macular edema, eyes with anterior uveitis cannot be distinguished from controls (p > 0.6).

conclusionThe deep retinal foveal avascular zone seems to be enlarged in eyes presenting with non-infectious posterior uveitis, both in the presence or absence of macular edema.

Indexed as

Visual AcuityAdolescentAdultCross-Sectional StudiesFluorescein AngiographyFollow-Up StudiesFovea CentralisFundus OculiHumansMacular EdemaMiddle AgedProspective StudiesRetinal VesselsTomography, Optical CoherenceUveitis, AnteriorUveitis, PosteriorAnterior uveitisFoveal avascular zoneNon-infectious uveitisOptical coherence tomography angiographyPosterior uveitis

Identifiers

PMID29980918
OpenAlexW2873863385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.