Evidence map›Paper›PMID 29980846›Full record

ArticleSurgery today2018

Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study.

Takahisa Ishikawa, Shingo Shimada, Moto Fukai, Taichi Kimura, Kouhei Umemoto, Kengo Shibata, Masato Fujiyoshi, Sunao Fujiyoshi, Takahiro Hayasaka, Norio Kawamura and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Surgery today, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Prospects of molecular hydrogen in cancer prevention and treatment.Journal of cancer research and clinical oncology · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Hydrogen: Potential Applications in Solid Organ Transplantation.Oxidative medicine and cellular longevity · 2021
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Takahisa IshikawaDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Shingo ShimadaDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Moto FukaiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan. db7m-fki@hotmail.co.jp.
Taichi KimuraLaboratory of Cancer Research, Department of Pathology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Kouhei UmemotoDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Kengo ShibataDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Masato FujiyoshiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Sunao FujiyoshiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Takahiro HayasakaDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Norio KawamuraDepartment of Transplant Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Nozomi KobayashiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Tsuyoshi ShimamuraDivision of Organ Transplantation, Central Clinical Facilities, Hokkaido University Hospital, Sapporo, Japan.
Akinobu TaketomiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-Ku, Sapporo, 060-8638, Japan.
Hokkaido University · JPHokkaido University Hospital · JP

Funding

Japan Society for the Promotion of Science Kakenhi 16K19885Japan Society for the Promotion of Science Kakenhi 17K10500Japan Society for the Promotion of Science Kakenhi 26670572
6 · The paper itself

Abstract

background and purposeWe reported previously that hydrogen gas (H

methodsRat livers were harvested after 30-min cardiac arrest and stored for 4 h in University of Wisconsin solution. The graft was reperfused with oxygenated buffer, with or without H

resultsIn the NT group, liver enzyme leakage, apoptosis, necrosis, energy depletion, redox status, impaired microcirculation, and bile production were indicative of severe IRI, whereas in the H

conclusionH

Indexed as

Liver TransplantationAnimalsCell DeathCold TemperatureCytoplasmDeathGasesGraft SurvivalHeart ArrestHydrogenIn Vitro TechniquesJNK Mitogen-Activated Protein KinasesLiverMaleMicrocirculationMitochondria, LiverGasesHydrogenJNK Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesDonation after cardiac deathHydrogen gasIschemia reperfusionLiverRat

Identifiers

PMID29980846
OpenAlexW2861742259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.