ArticleScientific reports2018
PID/WAG-mediated phosphorylation of the Arabidopsis PIN3 auxin transporter mediates polarity switches during gravitropism.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Diethyl ether anesthesia inhibits phototropic response inPlant signaling & behavior · 2026Article
- Deciphering the Protein Phosphorylation Dynamics Triggered by Seconds of Force Stimulation.Molecular & cellular proteomics : MCP · 2026Article
- SMXL3 controls multiple aspects of Arabidopsis development via EAR motif-dependent and -independent functions.The Plant journal : for cell and molecular biology · 2026Article
- An RbohC and RbohE-mediated ROS oscillatory circuit regulates root cap turnover in Arabidopsis.iScience · 2025Article
- The protein kinases KIPK and KIPK-LIKE1 suppress overbending during negative hypocotyl gravitropic growth in Arabidopsis.The Plant cell · 2025Article
- Auxin Controls Root Gravitropic Response by Affecting Starch Granule Accumulation and Cell Wall Modification in Tomato.Plants (Basel, Switzerland) · 2025Article
- Over 25 years of decrypting PIN-mediated plant development.Nature communications · 2024Review
- Article
- Article
- Genome Identification and Expression Profiling of theInternational journal of molecular sciences · 2024Article
- Article
- Antigravitropic PIN polarization maintains non-vertical growth in lateral roots.Nature plants · 2023Article
- Dynamic GOLVEN-ROOT GROWTH FACTOR 1 INSENSITIVE signaling in the root cap mediates root gravitropism.Plant physiology · 2023Article
- Design and synthesis of strong root gravitropism inhibitors with no concomitant growth inhibition.Scientific reports · 2023Article
- Plants in Microgravity: Molecular and Technological Perspectives.International journal of molecular sciences · 2022Review
- Fourteen Stations of Auxin.Cold Spring Harbor perspectives in biology · 2022Review
- The Characters of Non-Coding RNAs and Their Biological Roles in Plant Development and Abiotic Stress Response.International journal of molecular sciences · 2022Review
- Auxin Transporters-A Biochemical View.Cold Spring Harbor perspectives in biology · 2022Review
- MAG2 and MAL Regulate Vesicle Trafficking and Auxin Homeostasis With Functional Redundancy.Frontiers in plant science · 2022Article
- LAZY1-LIKE-mediated gravity signaling pathway in root gravitropic set-point angle control.Plant physiology · 2021Review
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7 authors.
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Abstract
Intercellular distribution of the plant hormone auxin largely depends on the polar subcellular distribution of the plasma membrane PIN-FORMED (PIN) auxin transporters. PIN polarity switches in response to different developmental and environmental signals have been shown to redirect auxin fluxes mediating certain developmental responses. PIN phosphorylation at different sites and by different kinases is crucial for PIN function. Here we investigate the role of PIN phosphorylation during gravitropic response. Loss- and gain-of-function mutants in PINOID and related kinases but not in D6PK kinase as well as mutations mimicking constitutive dephosphorylated or phosphorylated status of two clusters of predicted phosphorylation sites partially disrupted PIN3 phosphorylation and caused defects in gravitropic bending in roots and hypocotyls. In particular, they impacted PIN3 polarity rearrangements in response to gravity and during feed-back regulation by auxin itself. Thus PIN phosphorylation, besides regulating transport activity and apical-basal targeting, is also important for the rapid polarity switches in response to environmental and endogenous signals.
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