ArticleScientific reports2018
Antigenic characteristics and genomic analysis of novel EV-A90 enteroviruses isolated in Xinjiang, China.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Genetic variation, recombinant characteristics, and seroprevalence analysis of echovirus 3 causing severe and mild cases of hand, foot, and mouth disease in Guizhou Province.Microbiology spectrum · 2026Article
- Sequence-specific nanoparticle barcode strategy for multiplex human enterovirus typing.Nature communications · 2024Article
- A novel interspecies recombinant enterovirus (Enterovirus A120) isolated from a case of acute flaccid paralysis in China.Emerging microbes & infections · 2020Article
- Rules governing genetic exchanges among viral types from differentThe Journal of general virology · 2020Article
- Genomic epidemiology of coxsackievirus A16 in mainland of China, 2000-18.Virus evolution · 2020Article
- Molecular typing and characterization of a novel genotype of EV-B93 isolated from Tibet, China.PloS one · 2020Article
- Tracking echovirus eleven outbreaks in Guangdong, China: a metatranscriptomic, phylogenetic, and epidemiological study.Virus evolution · 2020Article
- Molecular Epidemiological, Serological, and Pathogenic Analysis of EV-B75 Associated With Acute Flaccid Paralysis Cases in Tibet, China.Frontiers in microbiology · 2020Article
- Multiple genotypes of Echovirus 11 circulated in mainland China between 1994 and 2017.Scientific reports · 2019Article
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10 authors.
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Abstract
Enterovirus A90 (EV-A90) is a novel serotype of enterovirus A species that is rarely reported. Here, we isolated five enteroviruses from patients with acute flaccid paralysis in Hotan and Kashgar cities in Xinjiang, China that were identified as EV-A90 by molecular typing. The VP1 sequences of these Xinjiang EV-A90 strains showed 88.4-89% nucleotide sequence identity to the prototype EV-A90 strain; however, genome analysis indicated complex recombination events in P2 and P3 regions. Next, the seroprevalence of EV-A90 was examined in 49 serum specimens collected in Hotan and Kashgar, and 37.5% were EV-A90 antibody positive (>1:8), with a geometric mean titre (GMT) of 1:10.47. The low positive rate and GMT suggest a low-level EV-A90 epidemic in Xinjiang. Two of the five Xinjiang EV-A90 strains were temperature sensitive, and three were temperature resistant, and a comparative genomics analysis suggested that an amino acid substitution (H1799Y) in the 3D
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