Evidence map›Paper›PMID 29980630›Full record

ReviewEssays in biochemistry2018

Coenzyme Q

Agape M Awad, Michelle C Bradley, Lucía Fernández-Del-Río, Anish Nag, Hui S Tsui, Catherine F Clarke

Open access · bronzeAbstract readReview
In one paragraph

Review in Essays in biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 131 citations in OpenAlex.

  1. Article
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  5. Review
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  14. Coenzyme Q10 and the Blood-Brain Barrier: An Overview.Journal of clinical medicine · 2025
    Review
  15. Identification of a newMolecular genetics and metabolism reports · 2025
    Article
  16. Article
  17. Article
  18. Understanding coenzyme Q.Physiological reviews · 2024
    Review
  19. Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Agape M AwadDepartment of Chemistry and Biochemistry, Molecular Biology Institute, UCLA, Los Angeles, CA 90095, U.S.A.
Michelle C BradleyDepartment of Chemistry and Biochemistry, Molecular Biology Institute, UCLA, Los Angeles, CA 90095, U.S.A.
Lucía Fernández-Del-RíoDepartment of Chemistry and Biochemistry, Molecular Biology Institute, UCLA, Los Angeles, CA 90095, U.S.A.
Anish NagDepartment of Chemistry and Biochemistry, Molecular Biology Institute, UCLA, Los Angeles, CA 90095, U.S.A.
Hui S TsuiDepartment of Chemistry and Biochemistry, Molecular Biology Institute, UCLA, Los Angeles, CA 90095, U.S.A.
Catherine F ClarkeDepartment of Chemistry and Biochemistry, Molecular Biology Institute, UCLA, Los Angeles, CA 90095, U.S.A. cathy@chem.ucla.edu.
University of California, Los Angeles · US

Funding

UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020
$21.7M
CHEMISTRY BIOLOGY INTERFACE TRAINING PROGRAMT32GM008496 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYNARD, HEATHER D · 1993 to 2019
$6.3M
NIGMS NIH HHS T32 GM007185NIGMS NIH HHS T32 GM008496
6 · The paper itself

Abstract

Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial respiratory electron transport and serves as an important antioxidant. In human and yeast cells, CoQ synthesis derives from aromatic ring precursors and the isoprene biosynthetic pathway.

Indexed as

AtaxiaGenes, FungalGenome, HumanHumansMitochondrial DiseasesMitochondrial ProteinsModels, BiologicalMuscle WeaknessMutationParabensSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsUbiquinone4-hydroxybenzoic acidcoenzyme Q10Mitochondrial ProteinsParabensSaccharomyces cerevisiae ProteinsUbiquinonecoenzyme Qmitochondrial dysfunctionSaccharomyces cerevisiaeubiquinone

Identifiers

PMID29980630
PMCPMC6056717
OpenAlexW2853306818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.