Evidence map›Paper›PMID 29980600›Full record

ArticleThe Journal of biological chemistry2018

Long-range function of secreted small nucleolar RNAs that direct 2'-

Jamie M Rimer, Jiyeon Lee, Christopher L Holley, Robert J Crowder, Delphine L Chen, Phyllis I Hanson, Daniel S Ory, Jean E Schaffer

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. snoCLASH Reveals Extensive snoRNA-mRNA Interaction Networks.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. RNA modifications and their role in gene expression.Frontiers in molecular biosciences · 2025
    Review
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jamie M RimerFrom the Department of Medicine.
Jiyeon LeeFrom the Department of Medicine.
Christopher L HolleyFrom the Department of Medicine.
Robert J CrowderFrom the Department of Medicine.
Delphine L ChenFrom the Department of Medicine.
Phyllis I HansonDepartment of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Daniel S OryFrom the Department of Medicine.
Jean E SchafferFrom the Department of Medicine, jschaff@wustl.edu.ORCID 0000-0002-4954-6659
Washington University in St. Louis · USMallinckrodt (Ireland) · IE

Funding

WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
PRINCIPLES IN CARDIVASCULAR RESEARCH TRAINING PROGRAMT32HL007081 · NHLBI · WASHINGTON UNIVERSITY · PI Abhinav Diwan, Karen Ellen Joynt Maddox · 1985 to 2026
$10.6M
CELLULAR MECHANISMS THAT PROMOTE OR PREVENT LIPOTOXICITYR01DK064989 · NIDDK · WASHINGTON UNIVERSITY · PI SCHAFFER, JEAN E. · 2003 to 2021
$5.8M
ANALYSIS OF ESCRT FUNCTION IN ENDOLYSOSOMAL TRAFFICKINGR01GM122434 · NIGMS · WASHINGTON UNIVERSITY · PI HANSON, PHYLLIS I · 2017 to 2024
$3.7M
Tissue Responses to Metabolic StressR01DK108357 · NIDDK · WASHINGTON UNIVERSITY · PI SCHAFFER, JEAN E. · 2016 to 2019
$2.0M
ZEISS LSM880 AIRYSCAN MICROSCOPE FOR SHARED BIOMEDICAL RESEARCHS10OD021629 · OD · WASHINGTON UNIVERSITY · PI FITZPATRICK, JAMES ALEXANDER · 2017 to 2017
$596k
NHLBI NIH HHS T32 HL007081NIDDK NIH HHS P30 DK020579NIDDK NIH HHS R01 DK064989NIDDK NIH HHS R01 DK108357NIGMS NIH HHS R01 GM122434NIH HHS S10 OD021629
6 · The paper itself

Abstract

Small nucleolar RNAs (snoRNAs) are noncoding RNAs that guide chemical modifications of structural RNAs. Whereas snoRNAs primarily localize in the nucleolus, where their canonical function is to target nascent ribosomal RNAs for 2'-

Indexed as

RNA Processing, Post-TranscriptionalAnimalsBiological TransportCell NucleolusCell NucleusFemaleHumansMaleMethylationMiceMice, KnockoutRibosomal ProteinsRNA, RibosomalRNA, Small NucleolarRibosomal ProteinsRNA, RibosomalRNA, Small NucleolarRpl13a protein, mouseexosome (vesicle)inflammationRNA methylationsecretionsmall nucleolar RNA (snoRNA)

Identifiers

PMID29980600
PMCPMC6109910
OpenAlexW2823527536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.