Evidence map›Paper›PMID 29980590›Full record

ArticleJournal of cell science2018

Regulation of PI4P levels by PI4KIIIα during G-protein-coupled PLC signaling in

Sruthi S Balakrishnan, Urbashi Basu, Dhananjay Shinde, Rajan Thakur, Manish Jaiswal, Padinjat Raghu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Phosphatidylinositol 4-phosphate; A minor lipid with multiple personalities.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2025
    Review
  4. Review
  5. Efr3b is essential for social recognition by modulating the excitability of CA2 pyramidal neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
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  8. Article
  9. Article
  10. Article
  11. Article
  12. Application of Fluorescent Proteins for Functional Dissection of theInternational journal of molecular sciences · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. A Genetic Screen inG3 (Bethesda, Md.) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sruthi S BalakrishnanNational Centre for Biological Sciences-TIFR, GKVK Campus, Bellary Road, Bangalore 560065, India.
Urbashi BasuNational Centre for Biological Sciences-TIFR, GKVK Campus, Bellary Road, Bangalore 560065, India.
Dhananjay ShindeNational Centre for Biological Sciences-TIFR, GKVK Campus, Bellary Road, Bangalore 560065, India.
Rajan ThakurNational Centre for Biological Sciences-TIFR, GKVK Campus, Bellary Road, Bangalore 560065, India.
Manish JaiswalTIFR Center for Interdisciplinary Science, Hyderabad 500107, India.
Padinjat RaghuNational Centre for Biological Sciences-TIFR, GKVK Campus, Bellary Road, Bangalore 560065, India praghu@ncbs.res.in.ORCID 0000-0003-3578-6413
National Centre for Biological Sciences · INTIFR Centre for Interdisciplinary Sciences · IN

Funding

DBT-Wellcome Trust India Alliance IA/S/14/2/501540Wellcome Trust
6 · The paper itself

Abstract

The activation of phospholipase C (PLC) is a conserved mechanism of receptor-activated cell signaling at the plasma membrane. PLC hydrolyzes the minor membrane lipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P

Indexed as

AnimalsCell MembraneDrosophilaDrosophila ProteinsEndoplasmic ReticulumFemaleMalePhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsSignal TransductionType C PhospholipasesDrosophila ProteinsPhosphatidylinositol 4,5-Diphosphatephosphatidylinositol 4-phosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsType C PhospholipasesDrosophilaPI4KIIIαPI4PPLC

Identifiers

PMID29980590
PMCPMC6104824
OpenAlexW2828776805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.