Evidence map›Paper›PMID 29980543›Full record

ArticleBMJ open2018

Accuracy of colorectal cancer ICD-9-CM codes in Italian administrative healthcare databases: a cross-sectional diagnostic study.

Francesco Cozzolino, Ettore Bidoli, Iosief Abraha, Mario Fusco, Gianni Giovannini, Paola Casucci, Massimiliano Orso, Annalisa Granata, Marcello De Giorgi, Paolo Collarile and 7 more

Open access · goldAbstract readValidation Study
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Colon Cancer Risk Following IntestinalJournal of clinical medicine research · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Detection of incident breast and colorectal cancer cases from an administrative healthcare database in Catalonia, Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Francesco CozzolinoHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.
Ettore BidoliCancer Epidemiology Unit, Centro di Riferimento Oncologico Aviano, Aviano, Italy.
Iosief AbrahaHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.ORCID 0000-0002-5440-775X
Mario FuscoRegistro Tumori Regione Campania, ASL NA 3 Sud, Brusciano, Italy.
Gianni GiovanniniHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.
Paola CasucciHealth ICT Service, Regional Health Authority of Umbria, Perugia, Italy.
Massimiliano OrsoHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.
Annalisa GranataRegistro Tumori Regione Campania, ASL NA 3 Sud, Brusciano, Italy.
Marcello De GiorgiHealth ICT Service, Regional Health Authority of Umbria, Perugia, Italy.
Paolo CollarileSOC Epidemiologia Oncologica, Centro di Riferimento Oncologico, Aviano, Italy.
Valerio CiulloRegistro Tumori Regione Campania, ASL NA 3 Sud, Brusciano, Italy.
Maria Francesca VitaleRegistro Tumori Regione Campania, ASL NA 3 Sud, Brusciano, Italy.
Roberto CirocchiDepartment of Digestive Surgery and Liver Unit, University of Perugia, Perugia, Italy.
Walter OrlandiDirezione Regionale Salute, Regional Health Authority of Umbria, Perugia, Italy.
Diego SerrainoCancer Epidemiology Unit, Centro di Riferimento Oncologico Aviano, Aviano, Italy.
Alessandro MontedoriHealth Planning Service, Regional Health Authority of Umbria, Perugia, Italy.
D.I.V.O. Group
Regione Campania · ITCentro di Riferimento Oncologico · ITAzienda Ospedaliera di Perugia · ITRegione Puglia · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

designA diagnostic accuracy study comparing ICD-9-CM codes (index test) for colorectal cancers with medical chart (as a reference standard). Case ascertainment based on neoplastic lesion(s) within the colon/rectum and histological documentation from a primary or metastatic site positive for colorectal cancer.

settingAdministrative databases from the Umbria region, Azienda Sanitaria Locale (ASL) Napoli 3 Sud (NA) region and Friuli Venezia Giulia (FVG) region.

participantsWe randomly selected 130 incident patients from each hospital discharge database, admitted between 2012 and 2014, having colorectal cancer ICD-9 codes located in primary position, and 94 non-cases, that is, patients having a diagnosis of cancer (ICD-9 140-239) other than colorectal cancer in primary position. OUTCOME MEASURES: Sensitivity, specificity and predictive values for 153.x code (colon cancer) and for 154.x code (rectal cancer).

resultsThe positive predictive value (PPV) for colon cancer diagnoses was 80% for Umbria (95% CI 73% to 87%), 81% for NA (95% CI 73% to 88%) and 80% for FVG (95% CI 72% to 87%).The sensitivity ranged from 98% to 99%, while the specificity ranged from 78% to 80% in the three units.For rectal cancer, the PPV was 84% for Umbria (95% CI 77% to 90%), 80% for NA (95% CI 72% to 87%) and 81% for FVG (95% CI 73% to 87%). The sensitivities ranged from 98% to 100%, while the specificity estimates from 79% to 82%.

conclusionsAdministrative databases in Italy can be a valuable tool for cancer surveillance as well as monitoring geographical and temporal variation of cancer practice.

Indexed as

Databases, FactualInternational Classification of DiseasesAdultClinical CodingColorectal NeoplasmsCross-Sectional StudiesFemaleHumansItalyMaleMiddle AgedSensitivity and SpecificityAdministrative DatabaseColorectal CancerIcd-9-cmPositive Predictive ValueSensitivity And SpecificityValidity

Identifiers

PMID29980543
PMCPMC6042611
OpenAlexW2824417486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.