ArticleBMC veterinary research2018
Effect of prolonged submaximal exercise on serum oxidative stress biomarkers (d-ROMs, MDA, BAP) and oxidative stress index in endurance horses.
Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- Effect of Antioxidant Supplementation on Systemic Oxidative Status in Breeding Stallions During Intensive Semen Collection.Animals : an open access journal from MDPI · 2026Article
- Kuwanon A fromAntioxidants (Basel, Switzerland) · 2026Article
- Transcriptomic and Proteomic Analysis of the Skeletal Muscle Revealed the Effects and Mechanism of Mulberry Leaf Flavonoids on Alleviating Exercise-Induced Muscle Damage in Mongolian Horses.Animals : an open access journal from MDPI · 2026Article
- Differences in Redox Biomarkers in Bronchoalveolar Lavage Fluid of Leisure Horses With and Without Severe Equine Asthma: Preliminary Results.Animals : an open access journal from MDPI · 2026Article
- Assessment of Blood Profiles and Pain in Sport Horses Undergoing Intrarectal Ozone Therapy.Veterinary medicine and science · 2026Article
- Training and race-induced coordination of oxidative stress markers in racehorses: insights from multivariate and univariate analyses.Journal of veterinary internal medicine · 2026Article
- Berberine Hydrochloride Reduces the Intracellular Survival ofBiomolecules · 2025Article
- The effect of heat and cold stress on oxidative stress of follicular microenvironment in beef cattle.The Journal of veterinary medical science · 2025Article
- Alleviation of Gypenosides on Peripheral and Central Fatigue via Anti-Inflammation, Anti-Oxidation and Neurotransmitter Regulation.Food science & nutrition · 2025Article
- Proteomic analysis emphasizes the adaptation of energy metabolism in horses during endurance races.BMC veterinary research · 2025Article
- The effect of long term astaxanthin supplementation on the antioxidant status of racing Arabian horses - preliminary study.Scientific reports · 2024Article
- Effects of maternal dietary supplementation with antioxidants on clinical status of mares and their foal.BMC veterinary research · 2024Article
- Identification of mulberry leaf flavonoids and evaluating their protective effects on HFrontiers in molecular biosciences · 2024Article
- Effects of transport stress on the oxidative index, apoptosis and autophagy in the small intestine of caprine.BMC veterinary research · 2023Article
- Changes in Acute Phase Response Biomarkers in Racing Endurance Horses.Animals : an open access journal from MDPI · 2022Article
- Myostatin Knockout Limits Exercise-Induced Reduction in Bovine Erythrocyte Oxidative Stress by Enhancing the Efficiency of the Pentose Phosphate Pathway.Animals : an open access journal from MDPI · 2022Article
- The Effect of Two Acute Bouts of Exercise on Oxidative Stress, Hematological, and Biochemical Parameters, and Rectal Temperature in Trained Canicross Dogs.Frontiers in veterinary science · 2022Article
- Screening of anti-chronic nonbacterial prostatitis activity of different extractions of the aerial part ofBiomedical reports · 2021Article
- Maternal and Neonatal Evaluation of Derived Reactive Oxygen Metabolites and Biological Antioxidant Potential in Donkey Mares and Foals.Animals : an open access journal from MDPI · 2021Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOxidative stress (OS) associated with an intense exercise may have a negative influence on equine health. The aim of this study was to determine the effects of endurance races on oxidative and antioxidative status of horses by evaluating changes in reactive oxygen metabolites (d-ROMs), malondialdehyde (MDA), biological antioxidant potential (BAP) and oxidative stress index (OSI) values. The study was carried out on 53 race starts (28 individual horses) competing at different endurance races according to distance (40 and 80 km) and difficulty (easy and demanding). Blood samples were taken before and after the race.
resultsCompared to levels of OS serum biomarkers before the race, an increase in values of d-ROMs (P < 0.01), MDA (P < 0.01), and BAP (P < 0.001), and a decrease in OSI (P < 0.001) have been noted after the race. Contrary to other measured biomarkers, BAP did not show significant individual effects of horses. Horses competing at shorter races have shown a significant change in d-ROMs (P = 0.002), BAP (P < 0.001) and OSI (P = 0.004), whereas those competing at longer races in MDA (P = 0.002), BAP (P < 0.001) and OSI (P < 0.001) post-race values. Endurance racing induced changes in values of d-ROMs, BAP and OSI during both easy and demanding races.
conclusionsChanges in all measured OS biomarkers indicate that prolonged aerobic exercise during endurance race could contribute to the imbalance between oxidants and antioxidants in horses, mainly characterised by a pronounced antioxidant response. Biological antioxidant potential was found to be the most reliable biomarker of OS in endurance horses in the present study.
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