Observational studyBMC pregnancy and childbirth2018
Perinatal outcomes in intrahepatic cholestasis of pregnancy with monochorionic diamniotic twin pregnancy.
Observational study in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association of serum total bile acid levels with gestational diabetes mellitus: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- A nomogram integrating dynamic total bile acid monitoring, medication history, and curative effect for preterm birth prediction in twin pregnancies with intrahepatic cholestasis of pregnancy.BMC pregnancy and childbirth · 2026Article
- A retrospective cohort study on perinatal outcomes of monochorionic and dichorionic twin pregnancies complicated by intrahepatic cholestasis of pregnancy.Scientific reports · 2025Observational
- The correlation between serum total bile acid and adverse perinatal outcomes in pregnant women with intrahepatic cholestasis of pregnancy (ICP) and non-ICP hypercholanemia of pregnancy.Annals of medicine · 2024Article
- Intrahepatic cholestasis of pregnancy: insights into pathogenesis and advances in omics studies.Hepatology international · 2024Review
- Clinical Management Guidelines for Intrahepatic Cholestasis of Pregnancy.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2024Article
- Early-onset intrahepatic cholestasis of pregnancy increased the incidence of gestational diabetes mellitus: a retrospective cohort study.Frontiers in medicine · 2024Article
- Perinatal outcomes associated with ICP in twin pregnancies were worse than singletons: an almost 5-year retrospective cohort study.BMC pregnancy and childbirth · 2022Article
- Unfolding newer concepts in placental pathology of obstetric cholestasis-a cause for prematurity.International journal of physiology, pathophysiology and pharmacology · 2022Review
- A meta-analysis of the prevalence of gestational diabetes in patients diagnosed with obstetrical cholestasis.AJOG global reports · 2021Article
- Value of Serum Glycocholic Acid and Total Bile Acids in Predicting Maternal and Perinatal Outcomes in Intrahepatic Cholestasis of Pregnancy.Journal of healthcare engineering · 2021Article
- Stillbirth and associated perinatal outcomes in obstetric cholestasis: a systematic review and meta-analysis of observational studies.European journal of obstetrics & gynecology and reproductive biology: X · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe primary aim of the study is to investigate the perinatal outcomes in intrahepatic cholestasis of pregnancy (ICP) with monochorionic diamniotic (MCDA) twin pregnancy.
methodsThis study is a retrospective observational study for women with ICP and MCDA twin pregnancy. Included cases were divided into mild ICP group (10-39 mmol/L) and severe ICP group (> = 40 mmol/L), whose perinatal outcomes were compared between this two groups and whose predictors of adverse perinatal outcomes were evaluated.
results37 cases and 21 cases are in mild and severe ICP group respectively, of which, the incidence of gestational diabetes mellitus (GDM) and iatrogenic preterm delivery in severe ICP group are higher than those in mild ICP group. Gestational age (GA) at diagnosis of ICP < 32 weeks is an independent risk factor for GA at delivery < 35 weeks and for composite adverse neonatal outcome. Total bile acids (TBA) > 40 mmol/l is an independent risk factor for meconium-stained amniotic fluid.
conclusionFor women with ICP and MCDA twin pregnancy, GA at diagnosis of ICP < 32 weeks and TBA > 40umol/L are associated with adverse perinatal outcomes.
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