Evidence map›Paper›PMID 29978718›Full record

ArticleCell transplantation2018

The Therapeutic Effects of Adipose-Derived Stem Cells and Recombinant Peptide Pieces on Mouse Model of DSS Colitis.

Reiko Iwazawa, Sayako Kozakai, Tsukasa Kitahashi, Kentaro Nakamura, Ken-Ichiro Hata

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Reiko Iwazawa1 Regenerative Medicine Research Laboratories, FUJIFILM Corporation, Kanagawa, Japan.
Sayako Kozakai1 Regenerative Medicine Research Laboratories, FUJIFILM Corporation, Kanagawa, Japan.
Tsukasa Kitahashi1 Regenerative Medicine Research Laboratories, FUJIFILM Corporation, Kanagawa, Japan.
Kentaro Nakamura1 Regenerative Medicine Research Laboratories, FUJIFILM Corporation, Kanagawa, Japan.ORCID 0000-0001-5530-8051
Ken-Ichiro Hata1 Regenerative Medicine Research Laboratories, FUJIFILM Corporation, Kanagawa, Japan.
Fujifilm (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell therapies using adipose-derived stem cells (ADSCs) have been used to treat inflammatory bowel disease (IBD) in human and dog. We previously reported the CellSaic technique, which uses a recombinant scaffold to enhance the efficacy of cell therapy. To examine whether this technique can be applied to cell therapy for colitis, we evaluated the efficacy of CellSaic in colitis mouse models. Colitis mouse models were developed by administering dextran sulfate sodium (DSS) to C57BL/6 mice for 7 days. Then CellSaic comprising human/canine ADSCs (1.2 × 10

Indexed as

Dextran SulfateStem Cell TransplantationAdipose TissueAnimalsBiocompatible MaterialsCell LineColitisColonDisease Models, AnimalDogsFemaleHumansMiceMice, Inbred C57BLStem CellsTissue ScaffoldsBiocompatible MaterialsDextran Sulfateadipose-derived stem cellsdextran sulfate sodium-induced colitis mouseinflammatory bowel diseaseveterinary therapy

Identifiers

PMID29978718
PMCPMC6168991
OpenAlexW2836868552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.