ArticleNeurosurgical review2019
Skull base versus non-skull base meningioma surgery in the elderly.
Article in Neurosurgical review, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Foramen magnum meningiomas: a systematic review and meta-analysis.Neurosurgical review · 2021Pooled it
- Derivation of a data-driven follow-up protocol for resected skull base meningiomas: a Bayesian analysis.Journal of neuro-oncology · 2026Article
- Extending voxel-based lesion mapping to neurosurgical oncology: applications in intracranial meningiomas.Frontiers in oncology · 2026Article
- Review
- Posterior cranial fossa meningiomas: Comparison of results between patients older and younger than 70 years.Brain & spine · 2024Article
- A nomogram for predicting the risk of major postoperative complications for patients with meningioma.Neurosurgical review · 2023Article
- Tumor Location Impacts the Development of Radiation Necrosis in Benign Intracranial Tumors.Cancers · 2023Article
- Different clinical and cytogenetic features of primary skull base meningiomas and non-skull base meningiomas.Journal of neuro-oncology · 2023Article
- De Novo Skull Base Atypical Meningioma: Incidence and Outcome.Journal of neurological surgery. Part B, Skull base · 2023Article
- Needs for a prediction model for each tumor location using features from T2WI, contrast-enhanced T1WI, and apparent diffusion coefficients to predict brain invasion of meningiomas.Neurosurgical review · 2022Article
- Review
- Review
- Perioperative Complication Profile of Skull Base Meningioma Resection in Older versus Younger Adult Patients.Journal of neurological surgery. Part B, Skull base · 2022Article
- Case Series of Skull Base Meningioma Resection in the Octogenarian Population.Journal of neurological surgery. Part B, Skull base · 2022Article
- Article
- Management of Skull-Base Meningiomas With Extracranial Extensions: Clinical Features, Radiological Findings, Surgical Strategies, and Long-Term Outcomes.Frontiers in neurology · 2022Article
- Symptom burden and surgical outcome in non-skull base meningiomas.Frontiers in oncology · 2022Article
- Article
- Article
- Lateral sphenoid wing meningiomas without bone invasion-still skull base surgery?Neurosurgical review · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To compare outcomes after surgery for skull base meningiomas (SBMs) with non-skull base meningiomas (NSBMs) in the elderly. Overall, 128 consecutive patients ≥ 70 years of age with intracranial SBMs operated between 1990 and 2010 were compared to 193 consecutive patients ≥ 70 years of age with NSBMs operated within the same time period. Median age at surgery was 75.0 years (mean 75.7, range 70.0-92.4). Follow-up was complete with median 4.7 years (mean 5.5, range 0-19). The female-to-male ratio was 2.8 for SBMs and 1.3 for NSBMs (p < 0.005). The groups had similar preoperative KPS (median 80, range 20-100), but SBMs presented significantly more frequently with raised ICP (RR = 2.2, p < 0.005) and less frequently with seizures (RR = 0.6, p < 0.05). WHO I was significantly more frequent in SBMs (p < 0.005). Gross-total resection (GTR) was less frequent in SBMs (63 vs 82%) (RR = 2.1, p < 0.0001). SBMs were similar to NSBMs with respect to neurological outcome at 6-12 months, reoperations for hematomas, postoperative infections, and 30-day mortality. Retreatment rates and time to retreatments were also similar. There were no differences between the two groups with respect to risk of retreatment and overall survival (OS) at 5, 10, 15, and 20 years. In elderly patients with SBMs selected to surgical treatment, the risks of surgery, risk of retreatment, and OS were similar to NBSMs. Therefore, surgery for SBMs may be considered as safe as NSBMs in the elderly population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.