Evidence map›Paper›PMID 29978268›Full record

Trial reportLasers in medical science2018

Evaluating the effect of photobiomodulation with a 940-nm diode laser on post-operative pain in periodontal flap surgery.

Mohadeseh Heidari, Reza Fekrazad, Farhad Sobouti, Mohammad Moharrami, Salman Azizi, Hanieh Nokhbatolfoghahaei, Maziar Khatami

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05447026 (The Adjunctive Use of Antimicrobial Photodynamic Therapy, Light-emitting-diode Photobiomodulation, and Ozone Therapy in Regenerative Treatment of Stage III Grade C Periodontitis), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05447026 nacompletednot on this map

The Adjunctive Use of Antimicrobial Photodynamic Therapy, Light-emitting-diode Photobiomodulation, and Ozone Therapy in Regenerative Treatment of Stage III Grade C Periodontitis

TypeinterventionalSponsorGazi UniversityRan2018 to 2022Enrolled48ConditionsPeriodontitis, Lasers, Ozone, Wound HealingArmsControl group, Antimicrobial photodynamic therapy (aPDT) group, LED photobiomodulation group, Topical ozone group
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  4. Type of study: original study.Lasers in medical science · 2025
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  11. Article
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  17. Effect of photobiomodulation on pain control after clinical crown lengthening surgery.Journal of advanced periodontology & implant dentistry · 2021
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  18. Article
  19. Effect of Photobiomodulation Therapy following Direct Pulp Capping on Postoperative Sensitivity by Thermal Stimulus: A Retrospective Study.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mohadeseh HeidariDepartment of Periodontology, Dental Faculty, Mazandaran University of Medical Sciences, Sari, Iran.
Reza FekrazadDepartment of Periodontology, Dental Faculty - Laser research center in medical Sciences, AJA University of Medical Sciences, Tehran, Iran.
Farhad SoboutiOrthodontic Department, Dental Faculty, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammad MoharramiDental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Salman AziziDental Faculty, Mazandaran University of Medical Sciences, Sari, Iran.
Hanieh NokhbatolfoghahaeiDental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. hanieh.nokhbe@gmail.com.ORCID http://orcid.org/0000-0002-6154-4349
Maziar KhatamiDepartment of Periodontology, Dental Faculty, Mazandaran University of Medical Sciences, Sari, Iran. mzkhatami@gmail.com.
Mazandaran University of Medical Sciences · IRTehran University of Medical Sciences · IRAja University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the efficacy of low-power of 940-nm diode laser on post-operative pain after undisplaced flap surgery. This randomized clinical trial study was conducted using a split-mouth design. The study participants comprised 30 patients who needed periodontal flap surgery for periodontal pockets on the same tooth on both sides of the mandible. One side of the mandible was subjected to undisplaced flap surgery plus treatment with a 940-nm diode laser, and on the contralateral side, the surgery was conducted without applying the laser. Patients received anti-inflammatory medication and analgesics after surgery. The patients were asked to report the number of analgesics they took and the pain they experienced each night for 1 week using a visual analogue scale. An independent-sample t test was used to compare the results between the two groups. Patients reported less pain on days 2, 3, 4, 5, 6, and 7 after surgery in the laser-treated group (p < 0.05). Furthermore, fewer analgesics were used in this group on days 3, 4, 5, 6, and 7 following the surgery (p < 0.05). The 940-nm diode laser with the settings used in this study could significantly reduce pain and the number of analgesics taken by patients after undisplaced flap surgery.

Indexed as

Low-Level Light TherapySurgical FlapsAdultAnalgesicsCase-Control StudiesFemaleHumansLasers, SemiconductorMaleMiddle AgedPain MeasurementPeriodontal PocketPostoperative PainTreatment OutcomeYoung AdultAnalgesics940-nm laserLow-level laser therapyPainPeriodontal flap surgeryPhotobiomodulation

Identifiers

PMID29978268
OpenAlexW2849229122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.