ArticleEndoscopy international open2018
Use of over-the-scope-clip (OTSC) improves outcomes of high-risk adverse outcome (HR-AO) non-variceal upper gastrointestinal bleeding (NVUGIB).
Article in Endoscopy international open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical efficacy of the over-the-scope clip device: A systematic review.World journal of gastroenterology · 2020Pooled it
- Clinical outcomes of over-the-scope-clip system for the treatment of acute upper non-variceal gastrointestinal bleeding: a systematic review and meta-analysis.BMC gastroenterology · 2019Pooled it
- Advancing hemostasis: A meta-analysis of novelWorld journal of gastrointestinal endoscopy · 2025Article
- Adverse events associated with the gold probe and the injection gold probe devices used for endoscopic hemostasis: A MAUDE database analysis.World journal of gastrointestinal endoscopy · 2024Article
- Insights on Over-the-Scope Clips.Gastroenterology & hepatology · 2022Article
- Endoscopic clipping in non-variceal upper gastrointestinal bleeding treatment.Clinical endoscopy · 2022Review
- New Trends and Advances in Non-Variceal Gastrointestinal Bleeding-Series II.Journal of clinical medicine · 2021Review
- Over-The-Scope Clip system as a first-line therapy for high-risk bleeding peptic ulcers: a retrospective study.Surgical endoscopy · 2021Observational
- Dieulafoy disease with gastric MALT lymphoma: A case report.Medicine · 2020Article
- Simulation-Based Mastery Learning for Practicing Gastroenterologists-Renewed Importance in the Era of COVID-19.The American journal of gastroenterology · 2020Review
- Over-the-scope clip vs epinephrine with clip for first-line hemostasis in non-variceal upper gastrointestinal bleeding: a propensity score match analysis.Endoscopy international open · 2020Article
- Over-the-Scope Clip to the Rescue! A Novel Tool for Refractory Acute Nonvariceal Upper Gastrointestinal Hemorrhage.Case reports in gastroenterologyArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND STUDY
aimsEndoscopic treatment of non-variceal upper gastrointestinal bleeding (NVUGIB) with high-risk adverse outcome (HR-AO) features has a high risk of failure. We studied the safety and efficacy of over-the-scope clips (OTSC) to treat these lesions. PATIENTS AND
methodsWe included patients who were treated using OTSC for NVUGIB from January 2015 to October 2017. We studied rebleeding and mortality rates and used the Rockall data and our institution's prior data for comparison. We used descriptive and chi-square statistics.
resultsWe studied 18 patients with 19 bleeding lesions: 9 (47 %) duodenal ulcers, 4 (21 %) Dieulafoy's lesion, 3 (16 %) gastric ulcer, and 3 (16 %) bleeding after gastric biopsy, gastric polypectomy and endoscopic ultrasound-guided fine-needle aspiration of peri-gastric mass. We applied OTSC as the first-line treatment in 10 (53 %) and as the second-line treatment in 9 (47 %) bleeding lesions. Continued bleeding after OTSC occurred in six patients, but we treated it successfully and achieved complete hemostasis in all patients. We found OTSC use significantly decreased (0 % vs. 53 %,
conclusionUse of OTSC is safe, efficacious and appears superior to standard treatment for HR-AO NVUGIB. OTSC should be considered as first-line treatment for HR-AO bleeding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.