Evidence map›Paper›PMID 29977969›Full record

ArticleOpen forum infectious diseases2018

Performance of TEM-PCR vs Culture for Bacterial Identification in Pediatric Musculoskeletal Infections.

James B Wood, Cheryl Sesler, Donald Stalons, Elena Grigorenko, Jonathan G Schoenecker, C Buddy Creech, Isaac P Thomsen

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

James B WoodDivision of Pediatric Infectious Diseases and Global Health, Department of Pediatrics, Indianapolis, Indiana.
Cheryl SeslerDiatherix-Eurofins, Huntsville, Alabama.
Donald StalonsDiatherix-Eurofins, Huntsville, Alabama.
Elena GrigorenkoDiatherix-Eurofins, Huntsville, Alabama.
Jonathan G SchoeneckerDepartment of Orthopaedics, Vanderbilt University School of Medicine, Nashville, Tennessee.
C Buddy CreechDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Isaac P ThomsenDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Eurofins (United States) · USVanderbilt University · USIndiana University – Purdue University Indianapolis · US

Funding

Evaluating the Functional Antibody Response to Pediatric S. aureus InfectionsK23AI113150 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI THOMSEN, ISAAC P · 2014 to 2018
$887k
NIAID NIH HHS K23 AI113150
6 · The paper itself

Abstract

Improved diagnostics are needed for children with musculoskeletal infections (MSKIs). We assessed the performance of target-enriched multiplex polymerase chain reaction (TEM-PCR) in children with MSKI. TEM-PCR was concordant with culture in pathogen identification and antibiotic susceptibility testing, while increasing the overall yield of pathogen detection. This technology has the potential to inform judicious antimicrobial use early in the disease course.

Indexed as

diagnosticsmusculoskeletal infectionsosteomyelitispediatricsseptic arthritis

Identifiers

PMID29977969
PMCPMC6007387
OpenAlexW2755650998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.