Evidence map›Paper›PMID 29977908›Full record

ArticleBioMed research international2018

Characterization of Atherosclerosis Formation in a Murine Model of Type IIa Human Familial Hypercholesterolemia.

Chiharu Miyajima, Takayuki Iwaki, Kazuo Umemura, Victoria A Ploplis, Francis J Castellino

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Modelling of atherosclerosis in genetically modified animals.American journal of translational research · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chiharu MiyajimaDepartment of Pharmacology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Takayuki IwakiDepartment of Pharmacology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.ORCID 0000-0003-3735-3718
Kazuo UmemuraDepartment of Pharmacology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
Victoria A PloplisThe W. M. Keck Center for Transgene Research and the Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
Francis J CastellinoThe W. M. Keck Center for Transgene Research and the Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
Hamamatsu University School of Medicine · JPUniversity of Notre Dame · US

Funding

Rescue of Hemostasis-deficiency StatesP01HL073750 · NHLBI · UNIVERSITY OF NOTRE DAME · PI CASTELLINO, FRANCIS J · 2004 to 2008
$8.8M
NHLBI NIH HHS P01 HL073750
6 · The paper itself

Abstract

A murine genetic model of LDL-cholesterol- (LDL-C-) driven atherosclerosis, based on complete deficiencies of both the LDL-receptor (

Indexed as

Disease Models, AnimalAnimalsAPOBEC-1 DeaminaseAtherosclerosisHumansHypercholesterolemiaHyperlipoproteinemia Type IIMaleMiceMice, KnockoutReceptors, LDLAPOBEC-1 DeaminaseApobec1 protein, mouseReceptors, LDL

Identifiers

PMID29977908
PMCPMC6011105
OpenAlexW2806150748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.