ArticleFrontiers in microbiology2018
Exposure to Arsenic Alters the Microbiome of Larval Zebrafish.
Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 62 citations in OpenAlex.
- Phenotypic heterogeneity in Pseudomonas aeruginosa virulence revealed through passive exposure in zebrafish (Danio rerio) and nematodes (Caenorhabditis elegans).Access microbiology · 2026Article
- Respiratory bacteriome and its predicted functional profiles in blue whales (Balaenoptera musculus).Scientific reports · 2025Article
- The Role ofToxics · 2025Review
- Toxic metals impact gut microbiota and metabolic risk in five African-origin populations.Gut microbes reports · 2025Article
- Arsenic Impairs Wound Healing Processes in Dermal Fibroblasts and Mice.International journal of molecular sciences · 2024Article
- Assessing the role of the gut microbiome at the interface between environmental chemical exposures and human health: Current knowledge and challenges.Environmental pollution (Barking, Essex : 1987) · 2022Review
- Impact of Heavy Metal Toxicity on the Gut Microbiota and Its Relationship with Metabolites and Future Probiotics Strategy: a Review.Biological trace element research · 2022Review
- Application of zebrafish in the study of the gut microbiome.Animal models and experimental medicine · 2022Review
- Bacteria communities and water quality parameters in riverine water and sediments near wastewater discharges.Scientific data · 2022Article
- Point-of-use carbon-block drinking water filters change gut microbiome of larval zebrafish.Environmental microbiology reports · 2022Article
- Chronic Embryo-Larval Exposure of Fathead Minnows to the Pharmaceutical Drug Metformin: Survival, Growth, and Microbiome Responses.Environmental toxicology and chemistry · 2022Article
- Passive exposure to cannabidiol oil does not cause microbiome dysbiosis in larval zebrafish.Current research in microbial sciences · 2021Article
- A Systematic Analysis of Metal and Metalloid Concentrations in Eight Zebrafish Recirculating Water Systems.Zebrafish · 2021Article
- Probiotic Bacteria with High Alpha-Gal Content Protect Zebrafish against Mycobacteriosis.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock.Scientific reports · 2021Article
- Arsenic induced redox imbalance triggers the unfolded protein response in the liver of zebrafish.Toxicology and applied pharmacology · 2020Article
- Article
- Whole genome sequence comparison of avian pathogenic Escherichia coli from acute and chronic salpingitis of egg laying hens.BMC veterinary research · 2020Article
- Arsenic disturbs the gut microbiome of individuals in a disadvantaged community in Nepal.Heliyon · 2020Article
- Gut microbiome: An intermediary to neurotoxicity.Neurotoxicology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to environmental toxins such as heavy metals can perturb the development and stability of microbial communities associated with human or animal hosts. Widespread arsenic contamination in rivers and riparian habitats therefore presents environmental and health concerns for populations living near sources of contamination. To investigate how arsenic affects host microbiomes, we sequenced and characterized the microbiomes of twenty larval zebrafish exposed to three concentrations of arsenic that are found in contaminated water-low (10 ppb), medium (50 ppb), and high (100 ppb) for 20 days. We found that even a small concentration of arsenic changed the overall microbial composition, structure and diversity of microbial communities, causing dysbiosis in developing larval zebrafish microbiota. In addition, we found that a high concentration of arsenic also increased the abundance of a class 1 integron, an integrase-dependent system facilitating the horizontal transfer of genes conferring resistance to heavy metals and antibiotics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.