ReviewFrontiers in endocrinology2018
Circadian Regulation of Glutamate Transporters.
Review in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Cross-sectional and longitudinal associations between circadian alignment and stroke in US adults.iScience · 2026Article
- Comparative Analysis of the Daily Liver Metabolomics of Asian Particolored Bat.Ecology and evolution · 2025Article
- Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host.Cancer cell · 2025Article
- Loss of Bmal1 impairs the glutamatergic light input to the SCN in mice.Frontiers in cellular neuroscience · 2025Article
- Circadian Pattern in Restless Legs Syndrome: Implications for Treatment Posology.Sleep science (Sao Paulo, Brazil) · 2024Article
- Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host.bioRxiv : the preprint server for biology · 2024Article
- Downregulated NPAS4 in multiple brain regions is associated with major depressive disorder.Scientific reports · 2023Article
- A Three-Way Interaction of Sex, PER2Genes · 2023Article
- The Circadian Clocks, Oscillations of Pain-Related Mediators, and Pain.Cellular and molecular neurobiology · 2023Review
- [Blood metabolites in preterm infants with retinopathy of prematurity based on tandem mass spectrometry: a preliminary study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Circadian clock synchrony and chronotherapy opportunities in cancer treatment.Seminars in cell & developmental biology · 2022Review
- Role of the cation-chloride-cotransporters in the circadian system.Asian journal of pharmaceutical sciences · 2021Review
- Study of influence of the glutamatergic concentration of [Translational psychiatry · 2021Article
- Day-Night Variations in the Concentration of Neurotransmitters in the Rat Lumbar Spinal Cord.Journal of circadian rhythms · 2021Article
- Astrocytic Modulation of Neuronal Activity in the Suprachiasmatic Nucleus: Insights from Mathematical Modeling.Journal of biological rhythms · 2020Article
- Circadian-Like Rhythmicity of Extracellular Brain Glutamate in Epilepsy.Frontiers in neurology · 2020Article
- Circadian entrainment by food and drugs of abuse.Behavioural processes · 2019Review
- Pin1 Is Regulated by CaMKII Activation in Glutamate-Induced Retinal Neuronal Regulated Necrosis.Frontiers in cellular neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
L-glutamate is the major excitatory amino acid in the mammalian central nervous system (CNS). This neurotransmitter is essential for higher brain functions such as learning, cognition and memory. A tight regulation of extra-synaptic glutamate levels is needed to prevent a neurotoxic insult. Glutamate removal from the synaptic cleft is carried out by a family of sodium-dependent high-affinity transporters, collectively known as excitatory amino acid transporters. Dysfunction of glutamate transporters is generally involved in acute neuronal injury and neurodegenerative diseases, so characterizing and understanding the mechanisms that lead to the development of these disorders is an important goal in the design of novel treatments for the neurodegenerative diseases. Increasing evidence indicates glutamate transporters are controlled by the circadian system in direct and indirect manners, so in this contribution we focus on the mechanisms of circadian regulation (transcriptional, translational, post-translational and post-transcriptional regulation) of glutamate transport in neuronal and glial cells, and their consequence in brain function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.