ReviewNature reviews. Neuroscience2018
Modelling microglial function with induced pluripotent stem cells: an update.
Review in Nature reviews. Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Characterizing the metabolomes of microglia, astrocytes and neurons in ageing and Alzheimer's brains.Nature cell biology · 2026Article
- Reimagining human-centric drug development with new approach methodologies.Science (New York, N.Y.) · 2026Review
- HIV Protein TAT Dysregulates Multiple Pathways in Human iPSCs-Derived Microglia.Life (Basel, Switzerland) · 2025Article
- Semaglultide targets Spp1Journal of neuroinflammation · 2025Article
- Article
- Modeling brain macrophage biology and neurodegenerative diseases using human iPSC-derived neuroimmune organoids.Frontiers in cellular neuroscience · 2023Article
- Alzheimer's disease-related transcriptional sex differences in myeloid cells.Journal of neuroinflammation · 2022Article
- The heterogeneity of microglial activation and its epigenetic and non-coding RNA regulations in the immunopathogenesis of neurodegenerative diseases.Cellular and molecular life sciences : CMLS · 2022Review
- Human iPSC co-culture model to investigate the interaction between microglia and motor neurons.Scientific reports · 2022Article
- Functional microglia derived from human pluripotent stem cells empower retinal organ.Science China. Life sciences · 2022Article
- Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems.Journal of neuroinflammation · 2022Article
- Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions.BMC biology · 2022Article
- Co-Culturing Microglia and Cortical Neurons Differentiated from Human Induced Pluripotent Stem Cells.Journal of visualized experiments : JoVE · 2021Article
- Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology.Stem cell reports · 2021Article
- Astrocytes and microglia in neurodegenerative diseases: Lessons from human in vitro models.Progress in neurobiology · 2021Review
- Stem-cell-derived human microglia transplanted into mouse brain to study human disease.Nature protocols · 2021Article
- Strategies and Tools for Studying Microglial-Mediated Synapse Elimination and Refinement.Frontiers in immunology · 2021Review
- Neural Differentiation of Mouse Embryonic Stem Cells-AnFrontiers in genetics · 2021Article
- Comparative analysis of human microglial models for studies of HIV replication and pathogenesis.Retrovirology · 2020Article
- Human iPSC-derived microglia: A growing toolset to study the brain's innate immune cells.Glia · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
It is becoming increasingly apparent that microglia, the immune cells of the CNS, and their peripheral counterparts, macrophages, have a major role in normal physiology and pathology. Recent technological advances in the production of particular cell types from induced pluripotent stem cells have led to an interest in applying this methodology to the production of microglia. Here, we discuss recent advances in this area and describe how they will aid our future understanding of microglia.
Indexed as
Identifiers
29977068What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.