ArticleNature communications2018
A biomimetic chiral-driven ionic gate constructed by pillar[6]arene-based host-guest systems.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 142 citations in OpenAlex.
- Supramolecular macrocyclic artificial ion channels for biomedical applications.Fundamental research · 2025Review
- Histamine-modulated wettability switching in G-protein-coupled receptor inspired nanochannel for potential drug screening and biosensing.Nature communications · 2025Article
- Ionic Bent-Core Pillar[Chemistry of materials : a publication of the American Chemical Society · 2024Article
- Based ATP-gating mechanism for detection of alkaline phosphatase in single-glass micropipettes functionalized by three-dimensional DNA network.Mikrochimica acta · 2024Article
- Applications of macrocycle-based solid-state host-guest chemistry.Nature reviews. Chemistry · 2023Review
- Chiral discrimination of cyclodecapeptide to anti-COVID-19 clinical candidates: a theoretical study.Structural chemistry · 2023Article
- Rational design of mesoporous chiral MOFs as reactive pockets in nanochannels for enzyme-free identification of monosaccharide enantiomers.Chemical science · 2023Article
- Polarization-sensitive optoionic membranes from chiral plasmonic nanoparticles.Nature nanotechnology · 2022Article
- Light-responsive nanochannels based on the supramolecular host-guest system.Frontiers in chemistry · 2022Review
- Structure and dynamics of nanoconfined water and aqueous solutions.The European physical journal. E, Soft matter · 2021Review
- Micrometer-scale transient ion transport for real-time pH assay in living rat brains.Chemical science · 2021Article
- Pillar[6]arene-based supramolecular polymeric materials constructedNanoscale advances · 2021Article
- Pre-regulation of the planar chirality of pillar[5]arenes for preparing discrete chiral nanotubes.Chemical science · 2021Article
- Editorial: Supramolecular Chirogenesis in Chemical and Related Sciences.Frontiers in chemistry · 2021Article
- Self-Assembly of Supramolecular Architectures by the Effect of Amino Acid Residues of Quaternary Ammonium Pillar[5]arenes.International journal of molecular sciences · 2020Article
- Biomimetic nanochannels for the discrimination of sialylated glycansChemical science · 2019Article
- A highly selective and recyclable NO-responsive nanochannel based on a spiroring opening-closing reaction strategy.Nature communications · 2019Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inspired by glucose-sensitive ion channels, herein we describe a biomimetic glucose-enantiomer-driven ion gate via the introduction of the chiral pillar[6]arene-based host-guest systems into the artificial nanochannels. The chiral nanochannels show a high chiral-driven ionic gate for glucose enantiomers and can be switched "off" by D-glucose and be switched "on" by L-glucose. Remarkably, the chiral nanochannel also exhibited a good reversibility toward glucose enantiomers. Further research indicates that the switching behaviors differed due to the differences in binding strength between chiral pillar[6]arene and glucose enantiomers, which can lead to the different surface charge within nanochannel. Given these promising results, the studies of chiral-driven ion gates may not only give interesting insight for the research of biological and pathological processes caused by glucose-sensitive ion channels, but also help to understand the origin of the high stereoselectivity in life systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.