ArticlePediatric research2018
The uncertain fate of the National Institutes of Health (NIH) pediatric research portfolio.
Article in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Recent trends and structural patterns in NIH pediatric research funding, 2015-2024.Pediatric research · 2026Article
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- Neuroinflammation and Pediatric Chronic Pain - A Review.Current pain and headache reports · 2026Review
- Developing and validating infant hedges for PubMed and Ovid MEDLINE: a Medical Library Association Pediatric Librarians Caucus initiative.Journal of the Medical Library Association : JMLA · 2025Article
- Bridging the Gap in FDA Approval for Pediatric Neuromodulation Devices.Children (Basel, Switzerland) · 2025Review
- Advocacy for children in global conflicts: the value of children in our world : How can we advocate for children as clinicians and researchers?Pediatric research · 2024Article
- Pediatric Drug Development: Reviewing Challenges and Opportunities by Tracking Innovative Therapies.Pharmaceutics · 2023Review
- Making the case for pediatric research: a life-cycle approach and the return on investment.Pediatric research · 2023Article
- Doing a PhD: ten golden rules.Pediatric research · 2023Article
- The state and future of pediatric research-an introductory overview : The state and future of pediatric research series.Pediatric research · 2023Article
- Modified e-Delphi Process for the Selection of Patient-Reported Outcome Measures for Children and Families With Type 1 Diabetes Using Continuous Glucose Monitors: Delphi Study.JMIR diabetes · 2022Article
- Value of children in our world.Pediatric research · 2022Article
- Reconsidering reviews: the role of scoping reviews in digital medicine and pediatrics.NPJ digital medicine · 2020Article
- Addressing Gaps in Pediatric Scientist Development: The Department Chair View of 2 AMSPDC-Sponsored Programs.The Journal of pediatrics · 2020Article
- Engagement in research among pediatric subspecialists at the time of enrollment in maintenance of certification, 2009-2016.Pediatric research · 2020Article
- Cultivating Research Skills During Clinical Training to Promote Pediatric-Scientist Development.Pediatrics · 2019Article
- The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.Developmental cell · 2019Review
- The uncertain fate of the National Institutes of Health (NIH) pediatric research portfolio: In support of an investment strategy to improve the public health of the nation through perinatal research.Pediatric research · 2018Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe amount of federal dollars allocated to improving the health of our pediatric population can serve as an indicator of the priority placed on child well-being. Although Congress has established novel mechanisms that marginally increase pediatric research funding, the pediatric research portfolio is facing an increasingly uncertain fate.
methodsThis work examines pediatric, perinatal and pediatric research initiative (PRI) spending using data collected by the NIH that uses the novel research, condition and disease categorization system. Further, this work reports on recent policy developments in pediatric biomedical research and offers recommendations to insulate this portfolio from future uncertainty.
resultsFederal support for pediatric research has declined with average annual growth rates of NIH pediatric spending dropping from 12.8% (FY 1998-2003) to 1.7% (FY 2004-2015). After taking into account Biomedical Research and Development Price Index growth, the pediatric research portfolio's purchasing power has declined by 15.9% (FY 2004-2015).
conclusionFederal support for pediatric biomedical research has plateaued in nominal terms and declined significantly in real terms. Future congressional action will be necessary to protect gains and to expand the capacity of the pediatric portfolio.
Indexed as
Identifiers
29976967What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.