ArticleScientific reports2018
Juvenile bovine bone is an appropriate surrogate for normal and reduced density human bone in biomechanical testing: a validation study.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 43 citations in OpenAlex.
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- Development of a low-cost external fixation system: an off-label solution for resource-limited settings.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- An osteoporotic bone model: developing and validating an ex-vivo bone demineralization protocol.JBMR plus · 2026Article
- Additively Manufactured Patient-Specific Trabecular Bone Imitations in Anatomical Bone Models for Preoperative Planning and Surgical Training: A Manufacturing Framework.Annals of biomedical engineering · 2026Article
- Recent advances in biomaterials for bone regeneration: Bridging innovation and clinical translation.Materials today. Bio · 2026Review
- Improved DNA recovery and STR profile development from weathered Bos taurus bones using demineralized bone slices.Journal of forensic sciences · 2025Article
- A graph model to describe the network connectivity of trabecular plates and rods.Frontiers in bioengineering and biotechnology · 2024Article
- Increased AGE Cross-Linking Reduces the Mechanical Properties of Osteons.JOM (Warrendale, Pa. : 1989) · 2024Article
- X-ray diffraction studies of a partially demineralized oriented cortical bone with the controlled depth of analysis.Heliyon · 2023Article
- Polymeric Orthosis with Electromagnetic Stimulator Controlled by Mobile Application for Bone Fracture Healing: Evaluation of Design Concepts for Medical Use.Materials (Basel, Switzerland) · 2022Article
- Kirschner Wire Fixation in Dorsally Displaced Distal Radius Fractures: A Biomechanical Evaluation.Journal of wrist surgery · 2022Article
- Endoscopy-assisted distal locking of an intramedullary nail: A new experimental technique to reduce radiation exposure during distal locking of the intramedullary nails.Joint diseases and related surgery · 2021Article
- Mineral Distribution Spatially Patterns Bone Marrow Stromal Cell Behavior on Monolithic Bone Scaffolds.Acta biomaterialia · 2020Article
- Xeno-Hybrid Bone Graft Releasing Biomimetic Proteins Promotes Osteogenic Differentiation of hMSCs.Frontiers in cell and developmental biology · 2020Article
- Surgical performance when inserting non-locking screws: a systematic review.EFORT open reviews · 2020Review
- Juvenile bovine bone is an appropriate surrogate for normal and reduced density human bone in biomechanical testing: a validation study.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthopaedic research necessitates accurate and reliable models of human bone to enable biomechanical discoveries and translation into clinical scenarios. Juvenile bovine bone is postulated to be a potential model of normal human bone given its dimensions and comparatively reduced ethical restrictions. Demineralisation techniques can reduce bone density and alter bone properties, and methods to model osteoporotic bone using demineralised juvenile bovine bone are investigated. Juvenile bovine long bones were quantitatively CT scanned to assess bone density. Demineralisation using hydrochloric acid (0.6, 1.2 and 2.4 M) was performed to create different bone density models which underwent biomechanical validation for normal and osteoporotic bone models. All long bones were found to have comparable features to normal human bone including bone density (1.96 ± 0.08 gcm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.