Evidence map›Paper›PMID 29976867›Full record

ReviewMolecules (Basel, Switzerland)2018

Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation-The Example of FimH.

Eva-Maria Krammer, Jerome de Ruyck, Goedele Roos, Julie Bouckaert, Marc F Lensink

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Molecular Modeling in Drug Design.Molecules (Basel, Switzerland) · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eva-Maria KrammerUnite de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique and the University of Lille, 50 Avenue de Halley, 59658 Villeneuve d'Ascq, France. eva-maria.krammer@univ-lille1.fr.ORCID 0000-0002-4821-2550
Jerome de RuyckUnite de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique and the University of Lille, 50 Avenue de Halley, 59658 Villeneuve d'Ascq, France. jerome.de-ruyck@univ-lille.fr.ORCID 0000-0003-4397-1870
Goedele RoosUnite de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique and the University of Lille, 50 Avenue de Halley, 59658 Villeneuve d'Ascq, France. goedele.roos@univ-lille.fr.
Julie BouckaertUnite de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique and the University of Lille, 50 Avenue de Halley, 59658 Villeneuve d'Ascq, France. julie.bouckaert@univ-lille1.fr.ORCID 0000-0001-8112-1442
Marc F LensinkUnite de Glycobiologie Structurale et Fonctionnelle, UMR 8576 of the Centre National de la Recherche Scientifique and the University of Lille, 50 Avenue de Halley, 59658 Villeneuve d'Ascq, France. marc.lensink@univ-lille.fr.ORCID 0000-0003-3957-9470
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Located at the tip of type I fimbria of

Indexed as

Adhesins, Escherichia coliAnti-Bacterial AgentsBacterial AdhesionDrug DesignEscherichia coliFimbriae ProteinsModels, MolecularMolecular Docking SimulationMolecular Dynamics SimulationProtein BindingAdhesins, Escherichia coliAnti-Bacterial AgentsFimbriae ProteinsfimH protein, E coliadhesionFimHligand bindingmolecular dockingmolecular dynamicsrational drug design

Identifiers

PMID29976867
PMCPMC6099838
OpenAlexW2810450426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.