Evidence map›Paper›PMID 29976758›Full record

ArticleThe Journal of biological chemistry2018

Dermatan sulfate epimerase 1 and dermatan 4-

Emil Tykesson, Antti Hassinen, Katarzyna Zielinska, Martin A Thelin, Giacomo Frati, Ulf Ellervik, Gunilla Westergren-Thorsson, Anders Malmström, Sakari Kellokumpu, Marco Maccarana

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Review
  6. Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. The glycocalyx: a central regulator of vascular function.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Review
  14. Article
  15. Review
  16. An Overview ofFrontiers in cell and developmental biology · 2021
    Review
  17. Article
  18. Article
  19. Role of Chondroitin Sulfation Following Spinal Cord Injury.Frontiers in cellular neuroscience · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Emil TykessonFrom the Department of Experimental Medical Science, Lund University, SE-221 00, Lund, Sweden.ORCID 0000-0002-0511-9831
Antti HassinenFaculty of Biochemistry and Molecular Medicine, University of Oulu, 90570 Oulu, Finland.
Katarzyna ZielinskaFrom the Department of Experimental Medical Science, Lund University, SE-221 00, Lund, Sweden.
Martin A ThelinFrom the Department of Experimental Medical Science, Lund University, SE-221 00, Lund, Sweden.
Giacomo FratiFrom the Department of Experimental Medical Science, Lund University, SE-221 00, Lund, Sweden.
Ulf EllervikDepartment of Chemistry, Lund University, SE-221 00, Lund, Sweden.
Gunilla Westergren-ThorssonFrom the Department of Experimental Medical Science, Lund University, SE-221 00, Lund, Sweden.
Anders MalmströmFrom the Department of Experimental Medical Science, Lund University, SE-221 00, Lund, Sweden.
Sakari KellokumpuFaculty of Biochemistry and Molecular Medicine, University of Oulu, 90570 Oulu, Finland.
Marco MaccaranaFrom the Department of Experimental Medical Science, Lund University, SE-221 00, Lund, Sweden, marco.maccarana@med.lu.se.ORCID 0000-0003-3549-8921
Lund University · SEUniversity of Helsinki · FIUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the biosynthesis of chondroitin/dermatan sulfate (CS/DS), a variable fraction of glucuronic acid is converted to iduronic acid through the activities of two epimerases, dermatan sulfate epimerases 1 (DS-epi1) and 2 (DS-epi2). Previous

Indexed as

AnimalsAntigens, NeoplasmChlorocebus aethiopsCOS CellsDermatan SulfateDNA-Binding ProteinsHumansIduronic AcidNeoplasm ProteinsRecombinant ProteinsSulfotransferasesAntigens, Neoplasmdermatan-4-sulfotransferase-1Dermatan SulfateDNA-Binding ProteinsDSE protein, humanIduronic AcidNeoplasm ProteinsRecombinant ProteinsSulfotransferaseschondroitin sulfateD4ST1dermatan sulfateDS-epi1DS-epi2epimeraseepimerizationglycobiologyglycosaminoglycanGolgi

Identifiers

PMID29976758
PMCPMC6120188
OpenAlexW2850624210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.