Evidence map›Paper›PMID 29976735›Full record

ReviewHaematologica2018

Preclinical human models and emerging therapeutics for advanced systemic mastocytosis.

Michel Arock, Ghaith Wedeh, Gregor Hoermann, Siham Bibi, Cem Akin, Barbara Peter, Karoline V Gleixner, Karin Hartmann, Joseph H Butterfield, Dean D Metcalfe and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Enhanced PIEZO1 expression in mast cells of mastocytosis skin lesions: Relevance to Darier's sign.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  4. Impact ofJournal of inflammation research · 2025
    Article
  5. Review
  6. Mutational Landscape ofVeterinary sciences · 2024
    Article
  7. Metformin: A potential adjunct for treatment of systemic mastocytosis.The journal of allergy and clinical immunology. Global · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 4 countries.

Michel ArockLBPA CNRS UMR8113, Ecole Normale Supérieure Paris-Saclay, Cachan, France arock@ens-cachan.fr.
Ghaith WedehLBPA CNRS UMR8113, Ecole Normale Supérieure Paris-Saclay, Cachan, France.
Gregor HoermannDepartment of Laboratory Medicine, Medical University of Vienna, Austria.
Siham BibiLBPA CNRS UMR8113, Ecole Normale Supérieure Paris-Saclay, Cachan, France.
Cem AkinMichigan Medicine Allergy Clinic, University of Michigan, Ann Arbor, MI, USA.
Barbara PeterLudwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
Karoline V GleixnerLudwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
Karin HartmannDepartment of Dermatology, University of Luebeck, Germany.
Joseph H ButterfieldMayo Clinic, Division of Allergic Diseases, Rochester, MN, USA.
Dean D MetcalfeLaboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD, USA.
Peter ValentLudwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
Ludwig Boltzmann Cluster for Cardiovascular Research · ATÉcole Normale Supérieure Paris-Saclay · FRMayo Clinic in Florida · USMedical University of Vienna · ATMichigan Medicine · USNational Institute of Allergy and Infectious Diseases · USSorbonne Université · FRUniversity of Lübeck · DE

Funding

The Pathogenesis, Diagnosis, And Treatment Of Systemic Mast Cell DisordersZIAAI000249 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI KOMAROW, HIRSH D · 2009 to 2025
$16.5M
6 · The paper itself

Abstract

Mastocytosis is a term used to denote a group of rare diseases characterized by an abnormal accumulation of neoplastic mast cells in various tissues and organs. In most patients with systemic mastocytosis, the neoplastic cells carry activating mutations in

Indexed as

Cell Line, TumorMast CellsMastocytosis, SystemicModels, BiologicalAnimalsHumans

Identifiers

PMID29976735
PMCPMC6278969
OpenAlexW2876204665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.