Evidence map›Paper›PMID 29976592›Full record

ArticleJournal of clinical microbiology2018

Metagenomics for Clinical Infectious Disease Diagnostics Steps Closer to Reality.

John P Dekker

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Delayed endophthalmitis caused byInternational journal of ophthalmology · 2024
    Article
  6. The MetaGens algorithm for metagenomic database lossy compression and subject alignment.Database : the journal of biological databases and curation · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Detection ofFrontiers in veterinary science · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John P DekkerDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA john.dekker@nih.gov.

Funding

Application of Genomic Approaches to Bacterial Pathogenesis and Mechanisms of Antimicrobial ResistanceZIAAI001249 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DEKKER, JOHN · 2019 to 2025
$13.7M
Next Generation Sequencing Methods in Molecular MicrobiologyZIACL080020 · CLC · CLINICAL CENTER · PI DEKKER, JOHN · 2015 to 2018
$0k
6 · The paper itself

Abstract

Metagenomics approaches based on shotgun next-generation sequencing hold promise for infectious disease diagnostics. Despite substantial challenges that remain, work done over the past few years justifies excitement about the potential for these approaches to transform how clinical pathogen identification and analysis are performed. In an article in this issue of the

Indexed as

MetagenomicsCommunicable DiseasesHigh-Throughput Nucleotide SequencingHumansLaboratoriesMolecular Diagnostic TechniquesPathology, MolecularSequence Analysis, DNA

Identifiers

PMID29976592
PMCPMC6113477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.